Clinical trials recruiting for Alzheimer Disease, Early Onset

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Multifocal tDCS-EEG Protocol for Improving Symptoms of Mild Cognitive Impairment and Early Dementia
  NCT06668610 · Phase: Not applicable (e.g. observational or device study) · Ages: 55 Years to 85 Years · Sex: All (male and female) · 1 location
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease
  NCT07328451 · Phase: Phase 1 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 4 locations
• Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy
  NCT05655195 · Phase: Not applicable (e.g. observational or device study) · Ages: 65 Years to 100 Years · Sex: All (male and female) · 1 location
• Donepezil Versus Non-drug Treatment in Alzheimer's Disease.
  NCT04661280 · Phase: Phase 3 · Ages: 50 Years and older · Sex: All (male and female) · 1 location
• GnRH Therapy on Cognition in Down Syndrome
  NCT04390646 · Phase: Phase 2, Phase 3 · Ages: 16 Years to 50 Years · Sex: All (male and female) · 1 location
• Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study
  NCT05573490 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 75 Years · Sex: All (male and female) · 1 location
• MECHANISMS OF NEURONAL RESILIENCE IN ALZHEIMER'S DISEASE AND ITS FOCAL VARIANTS: A PET/MR STUDY
  NCT04150198 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 80 Years · Sex: All (male and female) · 2 locations
• MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease
  NCT06099587 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal Study
  NCT02740634 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 80 Years · Sex: All (male and female) · 1 location
• NYSCF Scientific Discovery Biobank
  NCT06203106 · Phase: Not specified · Ages: 30 Days and older · Sex: All (male and female) · 1 location
• Network-based biOmarker Discovery of Neurodegenerative Diseases Using Multimodal Connectivity
  NCT06080659 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 80 Years · Sex: All (male and female) · 1 location
• Neuropsychological Profiles and Musical Engagement in Parkinson's and Alzheimer's Disease
  NCT06688968 · Phase: Not applicable (e.g. observational or device study) · Ages: 60 Years and older · Sex: All (male and female) · 3 locations
• Repurposing Nucleoside Reverse Transcriptase Inhibitors for Treatment of AD
  NCT04500847 · Phase: Phase 1 · Ages: 50 Years to 85 Years · Sex: All (male and female) · 2 locations
• Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease
  NCT07221344 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 3 locations
• The Dampness Syndrome of Chinese Medicine Cohort Study
  NCT05315895 · Phase: Not specified · Ages: 35 Years to 79 Years · Sex: All (male and female) · 1 location
• Transcranial Magnetic Stimulation to Slow Down Cognitive Decline in Alzheimer's Disease
  NCT07036328 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 85 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Alzheimer Disease, Early Onset often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Alzheimer Disease, Early Onset trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.