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A Study of AMDX-2011P in Participants With Alzheimer's Disease
NCT06514001 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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A Study of NTRX-07 in Participants With Alzheimer's Disease
NCT07058688 ·
Phase: Phase 2 ·
Ages: 65 Years to 80 Years ·
Sex: All (male and female) · 6 locations
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A Study of Oral EX039 in Subjects with Mild Alzheimer's Disease
NCT05413655 ·
Phase: Phase 2 ·
Ages: 50 Years to 80 Years ·
Sex: All (male and female) · 1 location
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A Study to Assess Safety and Tolerability and to Explore Efficacy of NSC001 in Mild to Moderate Alzheimer's Disease
NCT06995573 ·
Phase: Phase 1, Phase 2 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female) · 10 locations
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A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
NCT06540833 ·
Phase: Phase 2 ·
Ages: 55 Years and older ·
Sex: All (male and female) · 67 locations
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ALA-enriched Nutrition for Prevention of Cognitive Decline in APOE4 Older Adults
NCT07392723 ·
Phase: Phase 2 ·
Ages: 60 Years and older ·
Sex: All (male and female) · 1 location
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Allogeneic Adipose Tissue Derived-stem Cells in Alzheimer Disease
NCT07367815 ·
Phase: Phase 1, Phase 2 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female) · 1 location
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Alzheimer's Tau Platform: Master Protocol
NCT06957418 ·
Phase: Phase 2 ·
Ages: 50 Years to 80 Years ·
Sex: All (male and female) · 3 locations
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Assess Fibrin in Brains With AD/ADRD
NCT05336695 ·
Phase: Phase 1, Phase 2 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female) · 1 location
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Biomarker-based Trial of NPC-1 for Alzheimer's Pathology
NCT07236190 ·
Phase: Phase 2 ·
Ages: 55 Years and older ·
Sex: All (male and female) · 1 location
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Biomarkers of the Locus Coeruleus Nucleus: Links With Early Tau Pathology, Cognition and Alzheimer's Disease Risk
NCT07007208 ·
Phase: Phase 2 ·
Ages: 60 Years to 100 Years ·
Sex: All (male and female) · 1 location
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Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)
NCT07496918 ·
Phase: Phase 2 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female) · 1 location
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Bumetanide in Patients With Alzheimer's Disease
NCT06052163 ·
Phase: Phase 2 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female) · 1 location
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COMMETS- Combination MCI Metabolic Syndrome
NCT06072963 ·
Phase: Phase 2 ·
Ages: 60 Years to 90 Years ·
Sex: All (male and female) · 1 location
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Cannabidiol Medication Intervention Trial
NCT06014424 ·
Phase: Phase 2 ·
Ages: 55 Years and older ·
Sex: All (male and female) · 5 locations
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Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and Cognition
NCT05231798 ·
Phase: Phase 2 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female) · 1 location
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Clinical Trial on Agitation in Alzheimer's Dementia
NCT05543681 ·
Phase: Phase 2 ·
Ages: 60 Years and older ·
Sex: All (male and female) · 31 locations
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Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia
NCT07279740 ·
Phase: Phase 2 ·
Ages: No age limits stated ·
Sex: All (male and female) · 1 location
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DORA and LP in Alzheimer's Disease Biomarkers
NCT06274528 ·
Phase: Phase 2 ·
Ages: 65 Years and older ·
Sex: All (male and female) · 1 location
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Effects of THC-Free CBD Oil on Agitation in Patients With Alzheimer's Disease
NCT04436081 ·
Phase: Phase 2 ·
Ages: 50 Years to 90 Years ·
Sex: All (male and female) · 1 location
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Exercise to Improve Brain Health in Older African Americans
NCT05597124 ·
Phase: Phase 2 ·
Ages: 60 Years and older ·
Sex: All (male and female) · 1 location
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Fasudil Trial for Treatment of Early Alzheimer's Disease (FEAD)
NCT06362707 ·
Phase: Phase 2 ·
Ages: 50 Years to 100 Years ·
Sex: All (male and female) · 6 locations
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First-in-Human Evaluation of an Astrocytic Glutamate Transporter (EAAT2) PET Tracer in Dementia
NCT05374278 ·
Phase: Phase 1, Phase 2 ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female) · 1 location
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Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.
NCT06781333 ·
Phase: Phase 2 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female) · 1 location
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Large-coil Parietal Repetitive Transcranial Magnetic Stimulation (rTMS) for Alzheimer Disease (AD)
NCT06597942 ·
Phase: Phase 1, Phase 2 ·
Ages: 55 Years to 100 Years ·
Sex: All (male and female) · 1 location
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Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease
NCT04576793 ·
Phase: Phase 2 ·
Ages: 50 Years and older ·
Sex: All (male and female) · 1 location
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Nicotinic Acid for the Treatment of Alzheimer's Disease
NCT06582706 ·
Phase: Phase 1, Phase 2 ·
Ages: 60 Years to 85 Years ·
Sex: All (male and female) · 1 location
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Novel Augmentation of DAOIB and Antioxidant for Early Dementia
NCT06467539 ·
Phase: Phase 2 ·
Ages: 50 Years to 90 Years ·
Sex: All (male and female) · 1 location
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Open-Label Extension Protocol to SNK01-AD01 Study
NCT07228078 ·
Phase: Phase 2 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female) · 1 location
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Ozanimod in Patients With Alzheimer's Disease
NCT06862960 ·
Phase: Phase 2 ·
Ages: 55 Years to 80 Years ·
Sex: All (male and female) · 1 location
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Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease
NCT04902703 ·
Phase: Phase 2 ·
Ages: 60 Years to 85 Years ·
Sex: All (male and female) · 1 location
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Repurposing Siponimod for Alzheimer's Disease
NCT06639282 ·
Phase: Phase 2 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female) · 1 location
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Senicapoc in Alzheimer's Disease
NCT04804241 ·
Phase: Phase 2 ·
Ages: 55 Years to 85 Years ·
Sex: All (male and female) · 2 locations
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Sleep Healthy Using the Internet Mitigating Insomnia to Address Neurocognitive Difficulties (SHUTi MIND)
NCT05565833 ·
Phase: Phase 2 ·
Ages: 65 Years and older ·
Sex: All (male and female) · 1 location
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Sleep Trial to Prevent Alzheimer's Disease
NCT04629547 ·
Phase: Phase 2 ·
Ages: 65 Years and older ·
Sex: All (male and female) · 1 location
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Study of ARO-MAPT-SC in Healthy Participants and Participants With Early Alzheimer's Disease
NCT07221344 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female) · 3 locations
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Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
NCT06847321 ·
Phase: Phase 2 ·
Ages: 55 Years to 80 Years ·
Sex: All (male and female) · 38 locations
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Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
NCT06808984 ·
Phase: Phase 2 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female) · 78 locations
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Trial of CORT108297 to Attenuate the Effects of Acute Stress in the Allocortex (CORT-X)
NCT04601038 ·
Phase: Phase 2 ·
Ages: 55 Years and older ·
Sex: All (male and female) · 1 location
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UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
NCT03503331 ·
Phase: Phase 2 ·
Ages: 50 Years and older ·
Sex: All (male and female) · 1 location
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Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol
NCT07012993 ·
Phase: Phase 2 ·
Ages: 18 Years to 120 Years ·
Sex: All (male and female) · 1 location
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[18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DLB vs. AD
NCT06120049 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female) · 4 locations