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A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
NCT07033494 ·
Phase: Phase 2 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· New York: Albany, New Windsor, Queens
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A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
NCT07170150 ·
Phase: Phase 3 ·
Ages: 50 Years to 90 Years ·
Sex: All (male and female)
· New York: Rochester
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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
NCT07011745 ·
Phase: Phase 3 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: Brooklyn, Staten Island, Valley Stream
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A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
NCT07011732 ·
Phase: Phase 3 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: Inwood, New Windsor, Woodmere
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A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD
NCT05081596 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· New York: White Plains
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A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
NCT05552157 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: New York
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A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
NCT07717411 ·
Phase: Phase 3 ·
Ages: 55 Years to 80 Years ·
Sex: All (male and female)
· New York: Laurelton
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A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
NCT07169578 ·
Phase: Phase 3 ·
Ages: 50 Years to 90 Years ·
Sex: All (male and female)
· New York: Laurelton, New York, The Bronx
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A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
NCT07633470 ·
Phase: Phase 4 ·
Ages: 50 Years and older ·
Sex: All (male and female)
· New York: Albany
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A Study of a Potential Disease Modifying Treatment in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation
NCT06647498 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: New York
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A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
NCT05511363 ·
Phase: Phase 3 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: Manhasset, New York, Staten Island, Stony Brook
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A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-2)
NCT06126224 ·
Phase: Phase 3 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: New Hyde Park, Port Jefferson Station
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A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
NCT06585787 ·
Phase: Phase 3 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: New Windsor, Syracuse, Woodmere
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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
NCT06976216 ·
Phase: Phase 3 ·
Ages: 60 Years to 85 Years ·
Sex: All (male and female)
· New York: New York, Syracuse
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A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
NCT06976203 ·
Phase: Phase 3 ·
Ages: 60 Years to 85 Years ·
Sex: All (male and female)
· New York: Albany, Amherst, Buffalo, Lake Success
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A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
NCT06937229 ·
Phase: Phase 3 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: New Windsor, Staten Island, Woodmere
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ACP-204 in Adults With Alzheimer's Disease Psychosis
NCT06159673 ·
Phase: Phase 2, Phase 3 ·
Ages: 55 Years to 95 Years ·
Sex: All (male and female)
· New York: Amherst, Rochester, Syracuse, The Bronx
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Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
NCT06563895 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· New York: New York, Rosedale
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Autoimmune Features of Neurodegenerative Disorders
NCT04239079 ·
Phase: Not specified ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: New York
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Aβ Dynamics in LLMD
NCT05004987 ·
Phase: Phase 4 ·
Ages: 60 Years and older ·
Sex: All (male and female)
· New York: New York, Orangeburg
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Clinical Study of SNK01 in Participants With Moderate Alzheimer's Disease
NCT06189963 ·
Phase: Phase 1, Phase 2 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· New York: Albany
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Clinical Trial on Agitation in Alzheimer's Dementia
NCT05543681 ·
Phase: Phase 2 ·
Ages: 60 Years and older ·
Sex: All (male and female)
· New York: Amherst, Brooklyn, New York, Syracuse
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Daridorexant to Prevent Post-cardiotomy Delirium
NCT07217912 ·
Phase: Phase 2 ·
Ages: 60 Years and older ·
Sex: All (male and female)
· New York: Rochester
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Dementia Caregivers' Link to Assistance and Resources
NCT06860035 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: No age limits stated ·
Sex: All (male and female)
· New York: New York
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Designing Care Management for Hospice Transitions for Persons Living With Advanced Dementia
NCT07182357 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: New York
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Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia
NCT06584357 ·
Phase: Not specified ·
Ages: 60 Years to 90 Years ·
Sex: All (male and female)
· New York: Albany
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Dominantly Inherited Alzheimer Network (DIAN)
NCT00869817 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: New York
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Early Age-Related Hearing Loss Investigation (EARHLI)
NCT06174038 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years to 75 Years ·
Sex: All (male and female)
· New York: New York
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Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision
NCT06313853 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 65 Years and older ·
Sex: All (male and female)
· New York: Rochester
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Evaluating the Efficacy of the Pain Identification and Communication Toolkit
NCT06168604 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· New York: New York
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ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease
NCT03671889 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· New York: New York
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Genetic Studies of Early-onset Dementia
NCT04906863 ·
Phase: Not specified ·
Ages: 35 Years and older ·
Sex: All (male and female)
· New York: New York
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Innate Immunity Stimulation Via TLR9 in Early AD
NCT05606341 ·
Phase: Phase 1 ·
Ages: 60 Years to 85 Years ·
Sex: All (male and female)
· New York: New York
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Late Onset Alzheimer's Disease
NCT05010603 ·
Phase: Not specified ·
Ages: 55 Years and older ·
Sex: All (male and female)
· New York: New York
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Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease
NCT04576793 ·
Phase: Phase 2 ·
Ages: 50 Years and older ·
Sex: All (male and female)
· New York: New York
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Masupirdine for the Treatment of Agitation in Dementia of the Alzheimer's Type
NCT05397639 ·
Phase: Phase 3 ·
Ages: 50 Years to 90 Years ·
Sex: All (male and female)
· New York: Amherst, East Syracuse
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NYSCF Scientific Discovery Biobank
NCT06203106 ·
Phase: Not specified ·
Ages: 30 Days and older ·
Sex: All (male and female)
· New York: New York
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Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
NCT05980949 ·
Phase: Phase 3 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: Manhasset, New York, Stony Brook, Syracuse
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Open-label Extension Study in Participants With Early Alzheimer's Disease
NCT07105709 ·
Phase: Phase 2 ·
Ages: 50 Years to 85 Years ·
Sex: All (male and female)
· New York: Staten Island
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Phase 2 - Rhythmic Light Therapy for Alzheimer's Disease Patients
NCT05016219 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years and older ·
Sex: All (male and female)
· New York: Menands, New York
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Robotic-Enabled Microsurgical Intervention for Neurodegenerative Disease
NCT07178210 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: All (male and female)
· New York: Buffalo
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Safety Assessment of Leronlimab and Its Effect on Brain Inflammation in Alzheimer's Disease
NCT07553338 ·
Phase: Phase 2 ·
Ages: 50 Years and older ·
Sex: All (male and female)
· New York: New York
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Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
NCT07284472 ·
Phase: Phase 2, Phase 3 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: Brooklyn, New York
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Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
NCT07177352 ·
Phase: Phase 3 ·
Ages: 50 Years to 90 Years ·
Sex: All (male and female)
· New York: Laurelton, New York, Rochester, The Bronx
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Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
NCT06847321 ·
Phase: Phase 2 ·
Ages: 55 Years to 80 Years ·
Sex: All (male and female)
· New York: Albany, New York
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Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease
NCT06808984 ·
Phase: Phase 2 ·
Ages: 55 Years to 90 Years ·
Sex: All (male and female)
· New York: Buffalo, Manhasset, New Windsor, Staten Island
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Tau Networks in Psychotic Alzheimer's Disease
NCT05847192 ·
Phase: Not specified ·
Ages: 65 Years to 85 Years ·
Sex: All (male and female)
· New York: Manhasset
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Tele-Savvy for Latino Caregivers
NCT07290387 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: Rochester
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The Effects of Successful OSA Treatment on Memory and AD Biomarkers in Older Adults Study
NCT05988385 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 55 Years to 85 Years ·
Sex: All (male and female)
· New York: New York
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Triage Survey for Neurology Research Eligibility
NCT06104852 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· New York: New York
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Trial-Ready Cohort-Down Syndrome (TRC-DS)
NCT04165109 ·
Phase: Not specified ·
Ages: 25 Years to 55 Years ·
Sex: All (male and female)
· New York: Staten Island
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[18F]PI-2620 Phase 3 Histopathological Study
NCT05641688 ·
Phase: Phase 3 ·
Ages: 50 Years and older ·
Sex: All (male and female)
· New York: East Syracuse, Syracuse