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A Clinical Trial to Assess the Efficacy, Safety, and Tolerability of a Repeat Dose of Fasedienol Nasal Spray for the Acute Treatment of Anxiety in Adults With Social Anxiety Disorder
NCT06809179 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 9 locations
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A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety
NCT06820723 ·
Phase: Phase 2 ·
Ages: 21 Years to 65 Years ·
Sex: All (male and female) · 1 location
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A New Intervention to Improve Function in Veterans With Anxiety and Depression
NCT06188923 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 2 locations
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A Phase 2a Efficacy, Safety, Tolerability, and PK Study of SYT-510 in Participants With Generalized Anxiety Disorder
NCT07478744 ·
Phase: Phase 2 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female) · 1 location
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A Study of NTX-1472 in Social Anxiety Disorder
NCT07323784 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 11 locations
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A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
NCT07065240 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 61 locations
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Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease
NCT05685368 ·
Phase: Phase 1, Phase 2 ·
Ages: 14 Years to 21 Years ·
Sex: All (male and female) · 1 location
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Administration of Intranasal Midazolam for Anxiety in Palliative Care
NCT06330584 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 5 locations
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Adolescent Chatbot
NCT07094503 ·
Phase: Phase 2 ·
Ages: 13 Years to 19 Years ·
Sex: All (male and female) · 2 locations
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Assessing the Impact of Cannabidiol for Anxiety and Depression in Bipolar Disorder
NCT05457465 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Brain Network Changes Accompanying and Predicting Responses to Pharmacotherapy in OCD
NCT04131829 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Cannabidiol and Older Adult Cannabis Users
NCT06290063 ·
Phase: Phase 2 ·
Ages: 60 Years and older ·
Sex: All (male and female) · 1 location
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Cannabis for Palliative Care in Cancer
NCT06266611 ·
Phase: Phase 2 ·
Ages: 25 Years and older ·
Sex: All (male and female) · 1 location
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Clinical Trial on Agitation in Alzheimer's Dementia
NCT05543681 ·
Phase: Phase 2 ·
Ages: 60 Years and older ·
Sex: All (male and female) · 31 locations
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Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
NCT05474846 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Effect of CANnabidiol on Anxiety and GABAergic Function in Individuals With Fragile-X Syndrome
NCT06261502 ·
Phase: Phase 2 ·
Ages: 7 Years to 40 Years ·
Sex: All (male and female) · 1 location
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Effect of Probiotics "Psychobiotics" on Depression and Metabolic Syndrome in Saudi Arabia
NCT06765057 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Effects of Hemp-Derived Cannabinoids on Menopause Symptoms
NCT07393672 ·
Phase: Phase 2 ·
Ages: 40 Years to 60 Years ·
Sex: Female · 1 location
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Efficacy and Safety of Magnesium Vitamin B6 in First Episode Bipolar Disorder
NCT05837104 ·
Phase: Phase 2 ·
Ages: 18 Years to 50 Years ·
Sex: All (male and female) · 2 locations
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Efficacy of Nitrous Oxide in OCD: Pilot Study
NCT03826693 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Efficacy of Valbenazine for the Treatment of Trichotillomania in Adults
NCT05207085 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Enhancing Smoking Cessation for African American People Everywhere
NCT07024992 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol (R33)
NCT06273527 ·
Phase: Phase 2, Phase 3 ·
Ages: 21 Years to 55 Years ·
Sex: All (male and female) · 1 location
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Evaluating Buspirone to Treat Opioid Withdrawal
NCT05511909 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female) · 1 location
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Evaluating the Feasibility, Safety and Efficacy of Psychotherapy Assisted Psilocybin for Treatment of Severe OCD
NCT04882839 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Examining Mu Opioid Mechanisms of Ketamine's Rapid Effects in OCD (MKET2)
NCT05940324 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC.
NCT06145074 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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Family Acceptance Project Online (Pilot RCT)
NCT06839859 ·
Phase: Phase 2 ·
Ages: 14 Years and older ·
Sex: All (male and female) · 1 location
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Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety
NCT06595953 ·
Phase: Phase 2 ·
Ages: 8 Years to 17 Years ·
Sex: All (male and female) · 1 location
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Gut Microbiome Profiles in Patients with Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
NCT06799351 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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Interest of Medical Hypnosis in Anxious Patients Treated by Radiotherapy
NCT04513444 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Intranasal Dexmedetomidine for Acute Anxiety State in Adults
NCT07550881 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Investigating a Marijuana-based Compound as a Treatment for Anxiety in Autistic Adults
NCT06526208 ·
Phase: Phase 2 ·
Ages: 18 Years to 45 Years ·
Sex: All (male and female) · 1 location
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Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern City
NCT07673380 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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Lysergic Acid Diethylamide (LSD) in Palliative Care
NCT05883540 ·
Phase: Phase 2 ·
Ages: 22 Years and older ·
Sex: All (male and female) · 8 locations
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MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)
NCT05783817 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Mitigating PTSD-CUD After Sexual Assault
NCT05989841 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: Female · 6 locations
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Modulating Exercise Dosage to Improve Concussion Recovery
NCT05434130 ·
Phase: Phase 1, Phase 2 ·
Ages: 13 Years to 18 Years ·
Sex: All (male and female) · 3 locations
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Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV
NCT05570812 ·
Phase: Phase 2 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female) · 2 locations
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Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
NCT06706544 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Perinatal Depression & Anxiety (PDA) and Maternal Gut Microbiome
NCT06074250 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years to 43 Years ·
Sex: Female · 2 locations
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Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
NCT06073886 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 2 locations
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Pharmaco-Neuroimaging Studies of Approach/Avoidance Behaviors and Post-Mortem Studies: Pharmacological Manipulation
NCT05232032 ·
Phase: Phase 2 ·
Ages: 18 Years to 45 Years ·
Sex: All (male and female) · 1 location
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Pilot Study of RR-HNK in OCD
NCT06575075 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Pragmatic Trial of Obsessive-compulsive Disorder
NCT04539951 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Promoting Active Therapy: Path to Wellness
NCT06858189 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 2 locations
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Prospective Clinical Trial of Crisugabalin Capsules in the Treatment of Generalized Anxiety Disorder
NCT07330648 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder
NCT07072728 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female) · 6 locations
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Psilocybin-Assisted Psychotherapy in Patients With Advanced Cancer on Maintenance Therapy
NCT06200155 ·
Phase: Phase 2 ·
Ages: 25 Years and older ·
Sex: All (male and female) · 1 location
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Psilocybin-Assisted Therapy for Intergenerational Trauma
NCT06899165 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
NCT07002034 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female) · 32 locations
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RE104 Safety and Efficacy Study in Generalized Anxiety Disorder
NCT07489651 ·
Phase: Phase 2 ·
Ages: 18 Years to 74 Years ·
Sex: All (male and female) · 28 locations
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Roxadustat for Bone and Neuropsychiatric Aspects in Hemodialysis Patients
NCT06917950 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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SONATA LIFU for OCD
NCT07728994 ·
Phase: Phase 2 ·
Ages: 22 Years to 80 Years ·
Sex: All (male and female) · 1 location
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SSRI Antidepressant Fluoxetine Improving Immunotherapy Efficacy in Advanced Hepatobiliary Malignancy Patients With Depression and Anxiety
NCT07174947 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female) · 2 locations
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Safety and Efficacy of Pramipexole Treatment in Resistant Obsessive-Compulsive Disorder (OCD)
NCT06611592 ·
Phase: Phase 2 ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female) · 1 location
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Safety, Tolerability, and Preliminary Efficacy of Psilocybin Oral Solution in Adults With Generalized Anxiety Disorder
NCT06969170 ·
Phase: Phase 2 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female) · 1 location
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Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
NCT06376734 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 6 locations
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Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders
NCT06081348 ·
Phase: Phase 2 ·
Ages: 8 Years to 17 Years ·
Sex: All (male and female) · 7 locations
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Sleep and Stress Study
NCT07315516 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 1 location
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Study of Cannabidiol and Neuroimaging on Stress
NCT07278505 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 25 Years ·
Sex: All (male and female) · 1 location
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Study of Dextromethorphan in OCD and Related Disorders
NCT04899687 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 1 location
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Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
NCT06701903 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 51 locations
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Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
NCT06480383 ·
Phase: Phase 2 ·
Ages: No age limits stated ·
Sex: All (male and female) · 56 locations
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Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders
NCT00018057 ·
Phase: Phase 2 ·
Ages: 8 Years to 65 Years ·
Sex: All (male and female) · 4 locations
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Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder
NCT06846320 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female) · 52 locations
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TRIPS - Treatment to Improve Depression and/or Anxiety Using Psilocybin-assisted Psychotherapy in Cancer Survivors
NCT06801041 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female) · 2 locations
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iTBS+D-Cycloserine for Youth Suicide
NCT06121284 ·
Phase: Phase 2 ·
Ages: 18 Years to 24 Years ·
Sex: All (male and female) · 1 location