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A Clinical Study to Evaluate the Efficacy and Safety of Frevecitinib (KN-002) in Patients With Severe Asthma
NCT07532265 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Lancaster, San Jose
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A Phase II Study to Investigate Lung Function With 2 Different Doses of Inhaled Glycopyrronium Taken With BFF Compared to BFF in Participants of 4 to Less Than 12 Years of Age With Asthma
NCT07525375 ·
Phase: Phase 2 ·
Ages: 4 Years to 11 Years ·
Sex: All (male and female)
· California: Bakersfield, Lancaster, Long Beach, San Diego
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A Randomized, Double-Blind, Placebo-Controlled Trial on Efficacy and Safety of Fluticasone Propionate/Albuterol Sulfate Combination in Participants 12 Years and Older With Asthma
NCT06664619 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· California: Encinitas, Huntington Beach, La Palma, Laguna Niguel
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A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice
NCT07556159 ·
Phase: Not specified ·
Ages: 6 Years and older ·
Sex: All (male and female)
· California: California City, La Palma, Los Angeles, Newport Beach
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A Study of CDX-622 in Participants With Mild to Moderate Asthma
NCT07330778 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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A Study of Efficacy and Safety of Depemokimab Compared With Placebo in Adults and Adolescents With at Risk Type 2 Asthma
NCT07456033 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· California: Newport Beach
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A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma
NCT07323654 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Lancaster, Long Beach, Northridge, Redding
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A Study to Compare the Efficacy, Safety and Tolerability of FF/UMEC/VI With FF/VI in 12-17-year-olds With Asthma
NCT05757102 ·
Phase: Phase 3 ·
Ages: 12 Years to 17 Years ·
Sex: All (male and female)
· California: Bakersfield, Huntington Beach, Mission Viejo, Rolling Hills Estates
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A Study to Evaluate Brenipatide Compared With Placebo in Adult Participants With Uncontrolled Moderate to Severe Asthma
NCT07219173 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Newport Beach, Northridge, Rolling Hills Estates
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A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
NCT07276724 ·
Phase: Phase 3 ·
Ages: 12 Years to 80 Years ·
Sex: All (male and female)
· California: Northridge, Pasadena, Rancho Cucamonga, Valencia
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A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-2)
NCT07359846 ·
Phase: Phase 3 ·
Ages: 12 Years to 80 Years ·
Sex: All (male and female)
· California: Bakersfield, Inglewood, Lancaster, West Covina
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A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
NCT06023589 ·
Phase: Phase 3 ·
Ages: 5 Years to 11 Years ·
Sex: All (male and female)
· California: La Jolla, Long Beach, Orange, San Diego
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A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
NCT06977581 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· California: Lancaster, Newport Beach, Northridge, San Jose
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Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
NCT06932263 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Bakersfield, Huntington Beach, La Mesa, Loma Linda
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ENV-294 for Moderate-to-Severe Asthma: A 12-Week Study in Adults
NCT07301255 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: Los Angeles, San Jose, West Hills
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Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
NCT06307665 ·
Phase: Phase 3 ·
Ages: 12 Years to 17 Years ·
Sex: All (male and female)
· California: Huntington Beach, Long Beach, Madera, Mission Viejo
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Food Allergy Registry at a Single Site
NCT03539705 ·
Phase: Not specified ·
Ages: 0 Years to 100 Years ·
Sex: All (male and female)
· California: Palo Alto
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Leveraging Pharmacogenomics in Asthma for Predication, Mechanism and Endotyping
NCT06385236 ·
Phase: Phase 4 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: La Jolla
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Mechanism(s) of Airflow Limitation During Exacerbation of Asthma
NCT01225913 ·
Phase: Phase 4 ·
Ages: 10 Years to 80 Years ·
Sex: All (male and female)
· California: Lakewood
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Mechanism(s)of Airflow Limitation in Moderate-severe Persistent Asthma
NCT00576069 ·
Phase: Not specified ·
Ages: 10 Years to 95 Years ·
Sex: All (male and female)
· California: Lakewood
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Mechanistic Insights From Bronchoscopy Airway Samples
NCT06105710 ·
Phase: Not specified ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· California: San Francisco
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· California: Los Angeles, Palo Alto
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Phase 1 Study Evaluating Safety and Pharmacokinetics of ASY202 in Adults With Asthma
NCT07665892 ·
Phase: Phase 1 ·
Ages: 18 Years to 55 Years ·
Sex: All (male and female)
· California: Anaheim
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Randomised Clinical Trial to Investigate Efficacy and Safety of Benralizumab 30 mg SC as an add-on Therapy in Uncontrolled Eosinophilic Asthma Patients Treated With Medium-dose ICS-LABA Compared to Conventional Escalation to High-dose ICS-LABA Treatment
NCT06750289 ·
Phase: Phase 3 ·
Ages: 12 Years to 75 Years ·
Sex: All (male and female)
· California: Bakersfield, Inglewood, Modesto, Newport Beach
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Reducing Overuse of Antibiotics With Decision Support
NCT06788093 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 6 Months to 17 Years ·
Sex: All (male and female)
· California: Oakland, San Francisco
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Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
NCT03263130 ·
Phase: Not specified ·
Ages: 30 Years and older ·
Sex: All (male and female)
· California: Lakewood
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Smart Inhaler and Remote Asthma Management in Adolescents With Intellectual and Developmental Disabilities
NCT07746921 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 10 Years to 17 Years ·
Sex: All (male and female)
· California: Los Angeles
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Use of fenoTRACK Device for Monitoring Changes of Fractional Exhaled Nitric Oxide (FeNO) in Uncontrolled Asthma Subjects and Controlled Asthma Subjects
NCT07228026 ·
Phase: Not specified ·
Ages: 5 Years to 100 Years ·
Sex: All (male and female)
· California: Stockton
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Using a Smart Inhaler to Support Asthma Management in Adolescents With Intellectual and Developmental Disabilities
NCT06783101 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 10 Years to 17 Years ·
Sex: All (male and female)
· California: Los Angeles