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A Clinical Study of MK-2870 Alone or With Other Treatments to Treat Gastrointestinal Cancers (MK-9999-02A)
NCT06428409 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer
NCT05379595 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
NCT06662786 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
NCT06792695 ·
Phase: Phase 2 ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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A Study of PHN-012 in Patients With Advanced Solid Tumors
NCT07127874 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
NCT03093116 ·
Phase: Phase 1, Phase 2 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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A Study of STRO-004 in Adults With Refractory/Recurrent Metastatic Cancer
NCT07227168 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Cancer Experience Registry (CER) for Cancer Patients and Caregivers
NCT02333604 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
NCT05334069 ·
Phase: Not specified ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Collecting Blood and Tissue Sample Donations for Research for HIV/AIDS-Related Cancers
NCT05663502 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
NCT05174169 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Colonoscopy vs Stool Testing for Older Adults With Colon Polyps
NCT05612347 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 65 Years to 82 Years ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Evaluating Novel Therapies in ctDNA Positive GI Cancers
NCT05482516 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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FOG-001 in Locally Advanced or Metastatic Solid Tumors
NCT05919264 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
NCT05080673 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years to 70 Years ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia
NCT06073431 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors
NCT06586515 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
NCT03998202 ·
Phase: Not specified ·
Ages: 60 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
NCT05786924 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis
NCT06950385 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
NCT05855200 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers
NCT04485013 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
NCT04851119 ·
Phase: Phase 1, Phase 2 ·
Ages: 12 Months to 30 Years ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study
NCT05673148 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.
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Testing the Effectiveness of the Anti-cancer Drug Pidnarulex (CX-5461), in Combination With Another Anti-cancer Drug Cemiplimab (REGN2810), in Treating Refractory Microsatellite Stable Colorectal Cancer
NCT07147231 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· District of Columbia: Washington D.C.