Clinical trials recruiting for Colorectal Carcinoma

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Clinic-wide Intervention (Primary Care-GI Connect) for Improving Rates of Colonoscopy After Abnormal Fecal Immunochemical Test Result in Patients at Federally Qualified Health Centers
  NCT06568016 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 2 locations
• A Self-Monitoring Platform for Tracking Medication Safety and Concerns in Cancer Patients
  NCT07291414 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• A Study of MGC028 in Participants With Advanced Solid Tumors
  NCT06723236 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 7 locations
• A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation
  NCT05877599 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 23 locations
• A Web-Based Dyadic Intervention for Colorectal Cancer
  NCT05663203 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Addressing Disparities in Colorectal Cancer Screening in Black and Underserved Phoenix Communities
  NCT05447923 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years and older · Sex: All (male and female) · 1 location
• Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
  NCT06418204 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 934 locations
• CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors
  NCT06937567 · Phase: Early Phase 1 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 2 locations
• COLORECTUM+ Digital System for Postoperative Quality Improvement in Colorectal Cancer
  NCT06685497 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Changes in Reproductive and Sexual Health in People With Early Onset Colorectal Cancer
  NCT04812912 · Phase: Not specified · Ages: 18 Years to 50 Years · Sex: All (male and female) · 7 locations
• Clinical Research on the Treatment Model of Ambulatory Surgery for Colorectal Cancer
  NCT06637215 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Clinical Trial Evaluating the Activity of Zanidatamab for the Treatment of Patients With Solid Tumors With an Alteration of the HER2 Gene.
  NCT07192068 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Collection of Information to Better Understand Young Onset Colorectal Cancer
  NCT04489238 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 8 locations
• Confronting Cancer as a Community
  NCT06063928 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Culturally Adapting an Intervention to Increase Genetic Testing in African American Cancer Survivors
  NCT07436078 · Phase: Not applicable (e.g. observational or device study) · Ages: 20 Years to 79 Years · Sex: All (male and female) · 3 locations
• Encorafenib + Cetuximab Beyond Progression in Combination With FOLFIRI in Patients With BRAF V600E Mutated Metastatic Colorectal Cancer Progressing on Encorafenib + Cetuximab.
  NCT06640166 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Evaluating the Effects of an Exercise Intervention on the Gut Microbiota in Stage II-III Colorectal Cancer Survivors
  NCT05930496 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 70 Years · Sex: All (male and female) · 1 location
• Evaluation of PreveCol's Efficiency As a Second Line Method for the Early Colorectal Cancer Detection
  NCT06703632 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years to 69 Years · Sex: All (male and female) · 2 locations
• Immune Response Activation for the Treatment of Unresectable Metastatic Colorectal Cancer or CEA Positive Metastatic Breast Cancer
  NCT06130826 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Implementation of a ColoRectal Cancer Screening Tool in US Primary Care Practices - Usual Quality Improvement (10 Clinics) vs Normalization Process Theory-Participatory Learning in Action (10 Clinics)
  NCT06682650 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 75 Years · Sex: All (male and female) · 1 location
• Intrathecal Morphine Versus Epidural Analgesia for Open Colon Surgery
  NCT06935708 · Phase: Phase 4 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Irinotecan Hydrochloride Liposome Injection (Ⅱ) Combined with Fluorouracil, Folinic Acid, Vermofenib and Cetuximab in First-line Treatment of BRAFV600E Mutated Advanced Colorectal Cancer
  NCT06603376 · Phase: Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Irreversible Electroporation (IRE) for Treating Recurrent Pelvic Tumors (PELFIRE Study)
  NCT07782164 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC
  NCT04912765 · Phase: Phase 2 · Ages: 21 Years and older · Sex: All (male and female) · 1 location
• New bioMarkers tO straTIfy cOlorectal caNcer Referrals
  NCT07035691 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Organ Preservation in Rectal AdenoCa Using Hypofractionated Pelvic RT(Hypo-OPRA)
  NCT06991465 · Phase: Phase 2 · Ages: 18 Years to 90 Years · Sex: All (male and female) · 1 location
• PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer
  NCT05236972 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Patients With Rectal Cancer: a "Wait-and-see" Approach
  NCT03001362 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 90 Years · Sex: All (male and female) · 2 locations
• Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors
  NCT06218914 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 18 locations
• Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
  NCT05786924 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 27 locations
• Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery
  NCT06926374 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Role of Diet on the Microbiome of the Digestive System
  NCT04666727 · Phase: Not specified · Ages: 45 Years and older · Sex: All (male and female) · 1 location
• SCRT-CAPEOX-Serplulimab for MSS/pMMR Rectal Cancer With Oligometastases
  NCT06850103 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial
  NCT07618273 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 44 Years · Sex: All (male and female) · 1 location
• Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors
  NCT07030257 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 39 locations
• Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
  NCT04851119 · Phase: Phase 1, Phase 2 · Ages: 12 Months to 30 Years · Sex: All (male and female) · 42 locations
• Testing for Safety and Colorectal Cancer Preventive Effects of ONC201
  NCT05630794 · Phase: Phase 1 · Ages: 18 Years and older · Sex: All (male and female) · 5 locations
• Testing the Effects of Exercise on Colorectal Cancer Development After Treatment With Pelvic Radiation Therapy for Prostate Cancer
  NCT07790718 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years to 80 Years · Sex: Male · 2 locations
• The Cancer Connected Access and Remote Expertise Beyond Walls Program to Provide In-Home Cancer Treatment and Improve Treatment Satisfaction in Cancer Patients Living in the Florida Panhandle and Surrounding Areas
  NCT07285044 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• The Ohio State University (OSU) SCREEN Community Program
  NCT06666192 · Phase: Not applicable (e.g. observational or device study) · Ages: No age limits stated · Sex: All (male and female) · 1 location
• The Vanguard Study: Testing a New Way to Screen for Cancer
  NCT06995898 · Phase: Not applicable (e.g. observational or device study) · Ages: 45 Years to 75 Years · Sex: All (male and female) · 132 locations
• Zanidatamab Before Surgery for the Treatment of HER2 Positive Colon and Rectal Cancer in Patients Planned for Curative Intent Treatment
  NCT07405476 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 4 locations

Related conditions

Trials recruiting for Colorectal Carcinoma often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Colorectal Carcinoma trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.