Clinical trials recruiting for Early-Stage Breast Cancer

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• Adjuvant Trastuzumab Plus Neratinib in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer After Neoadjuvant Trastuzumab Plus Pertuzumab
  NCT05760612 · Phase: Phase 3 · Ages: 18 Years to 70 Years · Sex: Female · 1 location
• Adopting the MRD Strategy to Optimize Post-operation Adjuvant Therapies for Early Stage Breast Cancer
  NCT05345860 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Female · 3 locations
• BRE-04: Window of Opportunity Trial of Preoperative Low Dose Azacitidine in High-Risk Early Stage Breast Cancer
  NCT04891068 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Biolosion Combined Standard Neoadjuvant Therapy to Treat Triple-negative Breast Cancer
  NCT06768931 · Phase: Phase 2 · Ages: 18 Years and older · Sex: Female · 5 locations
• Breast Cancer Exercise Intervention Study
  NCT05957068 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 99 Years · Sex: Female · 3 locations
• COGNITION: Genomics-Guided Precision Oncology in Early High-Risk Breast Cancer
  NCT05906407 · Phase: Not specified · Ages: 18 Years to 80 Years · Sex: All (male and female) · 12 locations
• Cardiometabolic Screening Program
  NCT05386719 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Diagnostic HER2DX-guided Treatment for Patients wIth Early-stage HER2-positive Breast Cancer
  NCT06446882 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 29 locations
• Evaluating Minimal Residual Disease (MRD) Through Longitudinal Circulating Tumor DNA (ctDNA) Profiling in Breast Malignancies
  NCT07211178 · Phase: Not specified · Ages: 18 Years to 99 Years · Sex: All (male and female) · 16 locations
• Evaluating Omission of Granulocyte Colony-stimulating Factors in Breast Cancer Patients Receiving Paclitaxel Portion of Dose-dense Adriamycin-cyclophosphamide and Paclitaxel Chemotherapy
  NCT05753618 · Phase: Phase 4 · Ages: 18 Years and older · Sex: All (male and female) · 3 locations
• Evaluating the Use of a Medication 'Switch' vs Guideline-directed Interventions for Relieving Side Effects of Aromatase Inhibitors Among Breast Cancer Patients
  NCT07071038 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Exercise Therapy to Improve Cardiovascular Health in Post-Menopausal Women After Treatment for Early Stage Breast Cancer
  NCT04458532 · Phase: Not applicable (e.g. observational or device study) · Ages: 21 Years to 80 Years · Sex: Female · 2 locations
• Fudan University Shanghai Cancer Center Breast Cancer Precision Platform Series Study- Neoadjuvant Therapy
  NCT05582499 · Phase: Phase 2 · Ages: 18 Years to 70 Years · Sex: Female · 1 location
• Gut Microbiome, Adverse Effects, and Markers Through MEtabolic Reprogramming
  NCT06536881 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Female · 1 location
• I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer
  NCT01042379 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 42 locations
• Impact of Exercise on Quality of Life of EBC Patients on Treatment With Adjuvant AI With or Without CDK4/6 Inhibitors
  NCT07215364 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Female · 5 locations
• Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)
  NCT06150898 · Phase: Phase 2 · Ages: 18 Years to 70 Years · Sex: Female · 1 location
• PBI for Low-risk Breast Cancer
  NCT07814365 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 75 Years · Sex: Female · 1 location
• Pyrotinib Plus Capecitabine for Adjuvant Treatment of HER2 Positive Early-stage Breast Cancer
  NCT06035016 · Phase: Not specified · Ages: 18 Years to 75 Years · Sex: Female · 1 location
• Radiation After No Axillary Nodal Sampling
  NCT07723209 · Phase: Not applicable (e.g. observational or device study) · Ages: 40 Years and older · Sex: Female · 1 location
• Registry for Intra-Operative Radiotherapy During Breast Conserving Surgery in Patients With Early Stage Breast Cancer
  NCT04603209 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• SABER Study for Selected Early Stage Breast Cancer
  NCT04360330 · Phase: Not applicable (e.g. observational or device study) · Ages: 50 Years and older · Sex: Female · 1 location
• Statins for Reduction of Cardiac Toxicity in Patients Receiving HER2 Targeted
  NCT05559164 · Phase: Phase 2 · Ages: 18 Years and older · Sex: Female · 10 locations
• Targeted Axillary Dissection (TAD) in Early-stage Node Positive Breast Cancer
  NCT04671511 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: Female · 3 locations
• Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer
  NCT04553770 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 9 locations
• Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy With Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)
  NCT06902311 · Phase: Phase 2 · Ages: 50 Years and older · Sex: Female · 1 location
• ctDNA-Guided De-Escalation of Adjuvant Chemotherapy With Dalpiciclib in HR-Positive/HER2-Negative Breast Cancer
  NCT06970912 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: Female · 1 location

Related conditions

Trials recruiting for Early-Stage Breast Cancer often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Early-Stage Breast Cancer trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.