-
A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy
NCT03394365 ·
Phase: Phase 3 ·
Ages: No age limits stated ·
Sex: All (male and female)
· Florida: Gainesville, Miami
-
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
NCT05489705 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville
-
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
NCT06979362 ·
Phase: Phase 2 ·
Ages: 40 Years to 84 Years ·
Sex: All (male and female)
· Florida: Miami Lakes, Orlando, Winter Park
-
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
NCT07567001 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Clearwater, Coral Gables, Crystal River, Daytona Beach
-
A Safety and Tolerability Study of HJB647 in Heart Failure Participants With Reduced Ejection Fraction
NCT07465653 ·
Phase: Phase 1 ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Florida: Bradenton, Inverness, Jacksonville
-
A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
NCT07219511 ·
Phase: Phase 1 ·
Ages: 50 Years and older ·
Sex: All (male and female)
· Florida: Hialeah, Jacksonville, North Miami Beach, Pembroke Pines
-
A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
NCT06056297 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· Florida: St. Petersburg
-
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
NCT06024746 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Bradenton, Fort Lauderdale, Hialeah, Miami
-
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
NCT06008197 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Bradenton, Brooksville, Fort Lauderdale, Fort Myers
-
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
NCT06033950 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Bradenton, Hialeah, Jacksonville, Miami
-
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
NCT07761117 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Bradenton, Hallandale, Jacksonville, Lakeland
-
A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
NCT06991257 ·
Phase: Phase 2 ·
Ages: 18 Years to 79 Years ·
Sex: All (male and female)
· Florida: Boca Raton, Jacksonville, Miami, North Miami Beach
-
A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction
NCT07192952 ·
Phase: Phase 3 ·
Ages: Up to 18 Years ·
Sex: All (male and female)
· Florida: Gainesville, Hollywood
-
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
NCT07188805 ·
Phase: Phase 3 ·
Ages: 6 Months to 17 Years ·
Sex: All (male and female)
· Florida: Gainesville, Hollywood
-
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
NCT06935370 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Brandon, Daytona Beach, Doral, Gainesville
-
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
NCT06424288 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Boca Raton, Brandon, Clearwater, Daytona Beach
-
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
NCT06793371 ·
Phase: Phase 2 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Florida: Hialeah, Weston
-
AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
NCT06378632 ·
Phase: Not specified ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Florida: Crystal River, Jacksonville, Miami, Plantation
-
ANDREAS Registry (Assessment of Novel Drug-coated Balloon Revascularization: Effectiveness, Angiographic Outcomes, and Safety)
NCT07559903 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Fort Lauderdale
-
Alleviant ALLAY-HF Study
NCT05685303 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Florida: Gainesville, Jacksonville, Naples, Orlando
-
Alleviant ALLAY-HFrEF Study
NCT06812533 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Delray Beach, Pensacola, Tampa
-
Assessment of CCM in HF With Higher Ejection Fraction
NCT05064709 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Atlantis, Cutler Bay, Fort Lauderdale, Hollywood
-
Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
NCT07232030 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Clearwater, Jacksonville, Tallahassee, Tampa
-
Bridge to Lung Transplant With Trans-septal Extra-corporeal Membrane Oxygenation (ECMO) for Right Heart Failure From Pulmonary Hypertension
NCT06770023 ·
Phase: Phase 1 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Florida: Jacksonville
-
CCM OPEN HF Registry
NCT07112924 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Orlando, Tampa
-
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
NCT07207811 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gainesville
-
CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
NCT05996328 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Florida: Gainesville
-
CardiAMP Heart Failure II Trial for Patients With Ischemic Heart Failure With Reduced Ejection Fraction
NCT06258447 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years to 90 Years ·
Sex: All (male and female)
· Florida: Clearwater
-
Cardiogenic Shock Working Group Registry
NCT04682483 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Weston
-
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
NCT05485961 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Boca Raton, Bradenton, Brooksville, Coral Gables
-
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
NCT05677100 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Florida: Fort Lauderdale, Pensacola, Tallahassee, Tampa
-
ELEVATE-HFpEF Clinical Study
NCT06678841 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Florida: Panama City
-
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
NCT01790152 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Florida: Fort Myers, Gainesville, Hollywood, Jacksonville
-
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
NCT05714085 ·
Phase: Phase 2, Phase 3 ·
Ages: 29 Days to 17 Years ·
Sex: All (male and female)
· Florida: St. Petersburg
-
Feasibility and Efficacy Study of the CardioPulmonary Management (CPM) System in Patients With Chronic Heart Failure
NCT05650541 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Miami, Orlando
-
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
NCT06898515 ·
Phase: Phase 3 ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Florida: Gainesville
-
Gator SCALES-WHF: SubCutaneous Administration of Lasix to Eliminate Symptoms of Worsening Heart Failure
NCT06979726 ·
Phase: Phase 4 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Florida: Gainesville
-
HEMOTAG® Assessment for Short-term Outcomes of Heart Failure
NCT04149743 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Florida: Weston
-
Hearts on Fire: Targeting Inflammation in Heart Failure With Preserved Ejection Fraction
NCT07634640 ·
Phase: Early Phase 1 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Florida: Gainesville
-
His-Bundle Corrective Pacing in Heart Failure
NCT05265520 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Tampa
-
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
NCT06039176 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Florida: Gainesville
-
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
NCT06310031 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Florida: Gainsville, Orlando
-
Left vs Left Randomized Clinical Trial
NCT05650658 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Davie, Jacksonville, Miami Beach, Palm Beach Gardens
-
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
NCT07037459 ·
Phase: Phase 3 ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Florida: Altamonte Springs, Aventura, Boca Raton, Bradenton
-
NORM-HF Pivotal Study
NCT07574593 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville, Tampa
-
Observational Study Designed to Detect Decompensation of Congestive Heart Failure (dCHF) Using a Non-Invasive Wearable Device
NCT07350759 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Tampa
-
PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
NCT05934487 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Miami, Pensacola
-
Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Florida: Jacksonville
-
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
NCT06677060 ·
Phase: Phase 3 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Florida: Crystal River, Fort Lauderdale, Fort Myers, Gainesville
-
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
NCT00271180 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Florida: Bradenton, Clearwater, Hollywood, Jacksonville
-
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
NCT06777368 ·
Phase: Not specified ·
Ages: 18 Years to 105 Years ·
Sex: All (male and female)
· Florida: Clearwater, Fort Myers, Orlando, Tampa
-
Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
NCT07690436 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Jacksonville
-
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
NCT07069738 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Sarasota, Tampa
-
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
NCT06217302 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Florida: Orlando
-
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
NCT02901184 ·
Phase: Phase 3 ·
Ages: 50 Years to 99 Years ·
Sex: All (male and female)
· Florida: Fort Lauderdale
-
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
NCT06736574 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Florida: Clearwater, Fort Lauderdale, Hollywood, Jacksonville
-
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
NCT06597019 ·
Phase: Phase 3 ·
Ages: 6 Years to 11 Years ·
Sex: All (male and female)
· Florida: Boca Raton
-
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
NCT06307652 ·
Phase: Phase 3 ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· Florida: Altamonte Springs, Boca Raton, Bradenton, Clearwater
-
Supporting Health in Veterans With Heart Failure
NCT05839067 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gainesville
-
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
NCT06137807 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Delray Beach, Largo, Tampa
-
TRPC6 Characterization to Predict and Prevent Chemotherapy Related Cardiomyopathy and Heart Failure With Breast Cancer
NCT05507879 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gainesville, Jacksonville
-
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NCT03142152 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Delray Beach, Miami, Orlando, Palm Beach
-
The WiSE®-UP Registry (The WiSE System Utilization & Performance Registry)
NCT07098858 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Florida: Naples
-
Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders
NCT07221851 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· Florida: Orlando, St. Petersburg
-
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gainesville, Weston
-
Urine Sodium-Driven Diuretic Adjustment Strategy in Acute Decompensated Heart Failure
NCT07263035 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Lakeland
-
Utility of Thenar Near Infrared Spectroscopy (NIRS) in Pediatric Patients With Heart Failure
NCT02368041 ·
Phase: Not specified ·
Ages: Up to 25 Years ·
Sex: All (male and female)
· Florida: Gainesville
-
Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR
NCT05459233 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Hollywood
-
Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF
NCT03876223 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Florida: Gainesville