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A Phase 3 Study of Tabelecleucel for Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease After Failure With Rituximab or Rituximab and Chemotherapy
NCT03394365 ·
Phase: Phase 3 ·
Ages: No age limits stated ·
Sex: All (male and female)
· Illinois: Chicago, Maywood
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A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
NCT05489705 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
NCT07567001 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Hazel Crest, Orland Park, Peoria
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A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
NCT07219511 ·
Phase: Phase 1 ·
Ages: 50 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Hazel Crest, Peoria
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A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
NCT07795814 ·
Phase: Phase 2 ·
Ages: 30 Years to 84 Years ·
Sex: All (male and female)
· Illinois: Peoria
-
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
NCT06024746 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Glenview, Island Lake, Naperville, Peoria
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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
NCT06008197 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Glenview, Naperville, Peoria
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A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
NCT06033950 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Peoria
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A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
NCT07761117 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Champaign, Chicago, Gurnee, Melrose Park
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A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
NCT06991257 ·
Phase: Phase 2 ·
Ages: 18 Years to 79 Years ·
Sex: All (male and female)
· Illinois: Chicago, Evanston, Hazel Crest
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A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
NCT06935370 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Arlington Heights, Chicago, Hazel Crest, Libertyville
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A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
NCT06424288 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Arlington Heights, Chicago, Hazel Crest, Libertyville
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AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
NCT06793371 ·
Phase: Phase 2 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Illinois: Peoria
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AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM
NCT06378632 ·
Phase: Not specified ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Downers Grove, Naperville
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Alleviant ALLAY-HF Study
NCT05685303 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Naperville, Springfield
-
Alleviant ALLAY-HFrEF Study
NCT06812533 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Naperville
-
Aspirin and Hemocompatibility Events in Chronic Advanced Heart Failure Patients With Assist Device
NCT06655376 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
NCT07207811 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Glenview
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Cardiac Power Output in Cardiogenic Shock Patients
NCT05700617 ·
Phase: Early Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment
NCT05327062 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Cardiogenic Shock Working Group Registry
NCT04682483 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG
NCT07087613 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: O'Fallon, Springfield
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Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
NCT05677100 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Downers Grove, Elk Grove Village
-
ELEVATE-HFpEF Clinical Study
NCT06678841 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
NCT01790152 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Illinois: Chicago, Oak Lawn, Peoria
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Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
NCT04592445 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Springfield
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Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
NCT06898515 ·
Phase: Phase 3 ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Illinois: Oak Lawn
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HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
NCT05873634 ·
Phase: Not specified ·
Ages: 30 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
His-Bundle Corrective Pacing in Heart Failure
NCT05265520 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
NCT06039176 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Impact of Barostimulation on Hemodynamics in Adults With Heart Failure
NCT07335510 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure
NCT06526988 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
NCT06310031 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Illinois: Chicago
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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Illinois: Chicago, Mount Prospect, Peoria
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Left vs Left Randomized Clinical Trial
NCT05650658 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Evanston, Naperville
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Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
NCT07037459 ·
Phase: Phase 3 ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Illinois: Hazel Crest
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Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction
NCT06517186 ·
Phase: Not specified ·
Ages: 30 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
NCT06532890 ·
Phase: Not specified ·
Ages: Up to 18 Years ·
Sex: All (male and female)
· Illinois: Chicago
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PREACTIVE: Preconditioning Exercise Intervention to Improve Symptoms and Quality of Life in Comorbid Atrial Fibrillation and HFpEF
NCT07324772 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years to 99 Years ·
Sex: All (male and female)
· Illinois: Chicago
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PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
NCT05934487 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Downers Grove, Palos Park
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Illinois: Chicago
-
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
NCT06677060 ·
Phase: Phase 3 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Illinois: Champaign, Chicago, Gurnee, Island Lake
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Real World Effectiveness of the Cordella Pulmonary Artery Sensor System in Patients With Chronic Heart Heart Failure
NCT06783335 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Naperville
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Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
NCT07690436 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
NCT07069738 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Hinsdale, Naperville
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Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
NCT07059962 ·
Phase: Not specified ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
NCT06217302 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
NCT02901184 ·
Phase: Phase 3 ·
Ages: 50 Years to 99 Years ·
Sex: All (male and female)
· Illinois: Aurora, Chicago, Elk Grove Village, Peoria
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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
NCT06736574 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Illinois: Naperville
-
Study in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)
NCT06560762 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Study of the Progression of Chronic Cardiovascular Conditions
NCT07420907 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
NCT06307652 ·
Phase: Phase 3 ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· Illinois: Chicago, Glenview, Hazel Crest, North Chicago
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TEXT4HF: A Randomized Controlled Trial of a Tailored Text Messaging Intervention to Improve Self-Care in Older Adult Patients With Heart Failure
NCT06473532 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 50 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
NCT06137807 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Glenview, Palos Park
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The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NCT03142152 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Downers Grove, Naperville, Springfield
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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Oakbrook Terrace
-
UIC Multi-Ethnic DCM Registry
NCT07145138 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
NCT06641362 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
Use of Bedside Imaging and Community Health Workers for Early Screening and Referral of Pre-symptomatic Stage B Heart Failure in the Emergency Department
NCT06769880 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
NCT06895070 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
-
iCardia4HF: Multi-component mHealth Intervention for Patients With Heart Failure
NCT06205225 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago