-
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
NCT05489705 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville, Richmond, Roanoke
-
A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
NCT06979362 ·
Phase: Phase 2 ·
Ages: 40 Years to 84 Years ·
Sex: All (male and female)
· Virginia: Falls Church, Norfolk
-
A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
NCT07567001 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville, Manassas, Newport News, Norfolk
-
A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
NCT07795814 ·
Phase: Phase 2 ·
Ages: 30 Years to 84 Years ·
Sex: All (male and female)
· Virginia: Charlottesville
-
A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
NCT06024746 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Norfolk, Salem
-
A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
NCT06008197 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Norfolk, Richmond, Salem
-
A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
NCT06033950 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Norfolk, Richmond, Salem
-
A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
NCT07761117 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Arlington
-
A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
NCT06935370 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Manassas, Roanoke
-
A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
NCT06424288 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Manassas, Norfolk, Winchester
-
AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
NCT06793371 ·
Phase: Phase 2 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Virginia: Vienna
-
Alleviant ALLAY-HFrEF Study
NCT06812533 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Roanoke
-
Assessment of CCM in HF With Higher Ejection Fraction
NCT05064709 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Richmond
-
Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status
NCT06009276 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville
-
CCM OPEN HF Registry
NCT07112924 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Lynchburg
-
CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
NCT07207811 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Falls Church, Norfolk, Richmond
-
CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
NCT05996328 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Virginia: Richmond
-
Cardiogenic Shock Working Group Registry
NCT04682483 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Falls Church
-
Colchicine in Acutely Decompensated HFREF
NCT06286423 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville
-
Combined Dose-Finding and CV Outcomes Study With CSL300 (Clazakizumab) in Adult Subjects With ESKD Undergoing Dialysis (POSIBIL6ESKD)
NCT05485961 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Chesapeake, Fairfax, Hampton, Norfolk
-
Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator
NCT06964464 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Richmond
-
Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG
NCT07087613 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Norfolk
-
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
NCT05677100 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville, Richmond
-
ELEVATE-HFpEF Clinical Study
NCT06678841 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Virginia: Falls Church
-
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
NCT01790152 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Virginia: Richmond
-
Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having HFpEF
NCT04592445 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Virginia: Richmond
-
Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction
NCT07178145 ·
Phase: Phase 4 ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· Virginia: Charlottesville
-
Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
NCT06898515 ·
Phase: Phase 3 ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Virginia: Falls Church, Richmond
-
HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction
NCT05784753 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville
-
Hemodynamic Monitoring to Prevent Adverse Events foLlowing cardiOgenic Shock Trial
NCT04419480 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Falls Church
-
His-Bundle Corrective Pacing in Heart Failure
NCT05265520 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Richmond
-
In Search of Best Practices for Patients With Heart Failure and Secondary Mitral Regurgitation: An Evaluation of the Inova Heart Failure Treatment Algorithm
NCT06675448 ·
Phase: Not specified ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Virginia: Falls Church
-
Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
NCT06310031 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Virginia: Falls Church
-
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Virginia: Charlottesville, Norfolk
-
Left vs Left Randomized Clinical Trial
NCT05650658 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville, Falls Church, Newport News, Richmond
-
MYTHS - MYocarditis THerapy With Steroids
NCT05150704 ·
Phase: Phase 3 ·
Ages: 18 Years to 69 Years ·
Sex: All (male and female)
· Virginia: Charlottesville, Richmond
-
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
NCT07037459 ·
Phase: Phase 3 ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Virginia: Arlington, Falls Church, Manassas, Roanoke
-
Mechanistic Clinical Trial of Advanced Imaging for CRT
NCT03398369 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 20 Years to 90 Years ·
Sex: All (male and female)
· Virginia: Charlottesville
-
Optimal Pacing Rate for Cardiac Resynchronization Therapy
NCT06445439 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 90 Years ·
Sex: All (male and female)
· Virginia: Fairfax
-
PRIME HFrEF: Novel Exercise for Older Patients With Heart Failure With Reduced Ejection Fraction
NCT05609097 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 65 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville
-
PRagmatic Trial Of Messaging to Providers About Treatment of Heart Failure at Inova
NCT05433220 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Falls Church
-
Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
NCT06677060 ·
Phase: Phase 3 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Virginia: Burke, Charlottesville, Fairfax, Falls Church
-
Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
NCT00271180 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Virginia: Charlottesville, Falls Church
-
Prospective Observational Study of the ICD in Sudden Cardiac Death Prevention
NCT00733590 ·
Phase: Not specified ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Virginia: Richmond
-
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
NCT06777368 ·
Phase: Not specified ·
Ages: 18 Years to 105 Years ·
Sex: All (male and female)
· Virginia: Charlottesville, Falls Church, Norfolk
-
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
NCT04982419 ·
Phase: Phase 2, Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Richmond
-
Secondary Mitral Regurgitation Treatment With MitraClip and Assessment by Cardiac Magnetic Resonance
NCT07131631 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Falls Church
-
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
NCT06736574 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Virginia: Norfolk
-
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
NCT06597019 ·
Phase: Phase 3 ·
Ages: 6 Years to 11 Years ·
Sex: All (male and female)
· Virginia: Richmond
-
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
NCT06307652 ·
Phase: Phase 3 ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· Virginia: Falls Church, Newport News
-
TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
NCT06137807 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville, Norfolk, Roanoke
-
The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With FMR
NCT03142152 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville, Henrico, Norfolk, Richmond
-
The Effects of IL-1 Blockade on Inotrope Sensitivity in Patients With Heart Failure (AID-HEART)
NCT06062966 ·
Phase: Phase 1 ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Virginia: Richmond
-
Treating Heart Dysfunction Related to Cancer Therapy With Sacubitril/Valsartan
NCT05194111 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 120 Years ·
Sex: All (male and female)
· Virginia: Richmond
-
Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville
-
Ultra-High Frequency - Electrocardiogram (UHF-ECG) for the Diagnosis of Ventricular Electrical Dyssynchrony (VED)
NCT06641362 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Virginia: Charlottesville