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A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
NCT05489705 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
NCT07567001 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Seattle, Tacoma
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A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
NCT07795814 ·
Phase: Phase 2 ·
Ages: 30 Years to 84 Years ·
Sex: All (male and female)
· Washington: Seattle
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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
NCT06008197 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Spokane
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A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
NCT07761117 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Redmond
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A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
NCT06424288 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
NCT06793371 ·
Phase: Phase 2 ·
Ages: 40 Years to 85 Years ·
Sex: All (male and female)
· Washington: Seattle
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Alleviant ALLAY-HF Study
NCT05685303 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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Assessment of CCM in HF With Higher Ejection Fraction
NCT05064709 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Seattle, Vancouver
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CCM OPEN HF Registry
NCT07112924 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Vancouver
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CLEOPATTRA: A Research Study to Look at the Effects of Treatment With a Medicine Called Coramitug (NNC6019-0001) in People With Heart Failure Due to Transthyretin Amyloid (ATTR) Amyloidosis
NCT07207811 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Spokane
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Cardiogenic Shock Working Group Registry
NCT04682483 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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ELEVATE-HFpEF Clinical Study
NCT06678841 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Washington: Tacoma
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Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
NCT01790152 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Washington: Seattle, Spokane
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Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
NCT05714085 ·
Phase: Phase 2, Phase 3 ·
Ages: 29 Days to 17 Years ·
Sex: All (male and female)
· Washington: Seattle
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Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)
NCT06898515 ·
Phase: Phase 3 ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Washington: Seattle
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Left vs Left Randomized Clinical Trial
NCT05650658 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
NCT07037459 ·
Phase: Phase 3 ·
Ages: 18 Years to 99 Years ·
Sex: All (male and female)
· Washington: Puyallup
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Modulation of SERCA2a of Intra-myocytic Calcium Trafficking in Heart Failure With Reduced Ejection Fraction
NCT04703842 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Washington: Seattle
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Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
NCT06080074 ·
Phase: Phase 2 ·
Ages: 0 Years to 16 Years ·
Sex: All (male and female)
· Washington: Seattle
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PROACTIVE-HF-2 Trial Heart Failure NYHA Class II and III
NCT05934487 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Everett
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Washington: Seattle
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Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
NCT06677060 ·
Phase: Phase 3 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Washington: Puyallup, Redmond, Renton
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Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
NCT00271180 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: All (male and female)
· Washington: Olympia, Spokane
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Proof-of-concept of a Behavioral Intervention to Improve the Cardiovascular Health of People Living With HIV
NCT07105007 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
NCT06777368 ·
Phase: Not specified ·
Ages: 18 Years to 105 Years ·
Sex: All (male and female)
· Washington: Spokane
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Repurposing Valsartan May Protect Against Pulmonary Hypertension
NCT06053580 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Washington: Seattle
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Simulation Trial of Telemedical Support for Paramedics
NCT06441760 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 21 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
NCT06217302 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Washington: Seattle, Spokane
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Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
NCT06736574 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Washington: Spokane
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Study of the Clinical Impact of Surgical Correction of Tricuspid Insufficiency in Implantable LVAD Patients
NCT02537769 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Seattle
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Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
NCT06307652 ·
Phase: Phase 3 ·
Ages: 18 Years to 130 Years ·
Sex: All (male and female)
· Washington: Puyallup, Seattle, Tacoma
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TRIcvalve biCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
NCT06137807 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Multiple Locations, Seattle
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Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders
NCT07221851 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· Washington: Seattle
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XVIVO Heart Box (XHB) With Supplemented XVIVO Heart Solution (SXHS) Continued Access Protocol (CAP)
NCT06895070 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Washington: Seattle