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A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
NCT07285655 ·
Phase: Phase 3 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Illinois: Chicago
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A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
NCT06742723 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Champaign, Maywood, Rockford
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A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.
NCT07222917 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Champaign
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A Pivotal Study to Evaluate the Effectiveness of Isometric Handgrip Therapy in Elevated Blood Pressure and Hypertensive Subjects
NCT06843577 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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A Study of Mosliciguat in Combination With Inhaled Treprostinil in PH-ILD
NCT07333183 ·
Phase: Phase 2 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Illinois: Chicago
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A Study to Assess Adverse Events and Effectiveness of Gel Stent (XEN63) Implantation Using Ab Interno and Ab Externo Approaches in Adult Participants With Glaucoma
NCT06822738 ·
Phase: Phase 3 ·
Ages: 45 Years and older ·
Sex: All (male and female)
· Illinois: Peoria
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A Study to Evaluate the Pharmacodynamics of a Combination of QCZ484 and Inclisiran in Participants With Hypertension and Concomitant Hypercholesterolemia
NCT07610278 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Illinois: Chicago, Niles
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Aspirin and Preeclampsia
NCT04479072 ·
Phase: Phase 4 ·
Ages: 18 Years to 45 Years ·
Sex: Female
· Illinois: Chicago
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BradycArdia paCemaKer With AV Interval Modulation for Blood prEssure treAtmenT
NCT06059638 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Clarifying the Optimal Application of SLT Therapy Trial
NCT04967989 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Orland Park, Peoria
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Community Intervention to Reduce CardiovascuLar Disease in Chicago
NCT04755153 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 89 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Community-based Approach to Lowering Stress Through Mindfulness
NCT06987799 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Conical Forearm and Cylindrical Upper Arm Non-Invasive Blood Pressure (NIBP) Measurements in Pregnant Patients
NCT06466161 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Illinois: Chicago
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DeciPHer-ILD: A Real-world Patient Registry in Group 3 Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
NCT06388421 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Maywood, Oak Lawn
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Deep Learning Detection of Pulmonary Hypertension and Low Ejection Fraction Via Digital Stethoscope and 3-Lead ECG
NCT07087613 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: O'Fallon, Springfield
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E3 Hypertension - A Team-based, Multidisciplinary Model in Addressing Barriers to Hypertension Control
NCT06899750 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
NCT07064473 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Lombard, Oak Lawn
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Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
NCT06468202 ·
Phase: Phase 4 ·
Ages: 14 Years to 35 Years ·
Sex: Female
· Illinois: Chicago
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Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost
NCT06883123 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Springfield
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Evaluation of Efficacy and Safety of Iloperidone for the Treatment of Participants With Uncontrolled Hypertension
NCT07090161 ·
Phase: Phase 2 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Illinois: Oak Brook, Tinley Park
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Examining Digital Health Care Delivery Models Through Medicaid Collaborative
NCT05555095 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Peoria
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FIM+DASH: Food is Medicine Intervention to Promote Healthy Eating and Blood Pressure Control
NCT07332741 ·
Phase: Phase 2 ·
Ages: No age limits stated ·
Sex: All (male and female)
· Illinois: Chicago
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Global Paradise System US Post Approval Study
NCT06297291 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Springfield
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Human/Machine Interface: What the HeartMate 3 ® Device Tells Us About the Future
NCT06039176 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
NCT06397456 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Interactive Computer-adaptive Chronic Kidney Disease Education Program
NCT06364358 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Illinois: Chicago
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LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398 ·
Phase: Phase 3 ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Illinois: Chicago, Mount Prospect, Peoria
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MegaNatural BP® GSE on Blood Pressure and Cardiometabolic Risk Factors
NCT06555952 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 60 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Mobilizing Community Hypertension Access Pilot
NCT07547345 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
NCT06911632 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Open-label Extension Study of Seralutinib in Adult Subjects With PAH (PROSERA-EXT)
NCT06274801 ·
Phase: Phase 3 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Optimizing Sustainable Cuff Access and Training Pathways for Self-Measured Blood Pressure Monitoring in Primary Care
NCT07693699 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Merrionette Park, Oak Lawn
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Perimetric Testing With Virtual Reality
NCT06549010 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 25 Years to 70 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404 ·
Phase: Not specified ·
Ages: 0 Years to 20 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Predict Severe Traumatic Brain Injury
NCT06966713 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Preparing FIM-BCS - A Lifestyle Modification for African-American Breast Cancer Survivors
NCT06504914 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 99 Years ·
Sex: Female
· Illinois: Chicago
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Preventative Screening and Health Coaching in a Food Insecure Population
NCT06907524 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 40 Years to 75 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia
NCT06220721 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: Female
· Illinois: Chicago
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Study of Efficacy and Safety of Tonlamarsen in Participants With a Recent Hospitalization and a Concurrent Episode of Acute Severe Hypertension
NCT07511361 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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Study of the Progression of Chronic Cardiovascular Conditions
NCT07420907 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago
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THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
NCT06559891 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 22 Years to 75 Years ·
Sex: All (male and female)
· Illinois: Elk Grove Village, Springfield
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The REACH-OUT Trial
NCT07540143 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 44 Years ·
Sex: Female
· Illinois: Chicago
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To Evaluate the Safety and Efficacy of MANP in Subjects With Difficult to Control/ Resistant Hypertension
NCT06343298 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Illinois: Chicago
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Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
NCT06526195 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Chicago, Oakbrook Terrace
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Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project
NCT06004674 ·
Phase: Phase 2 ·
Ages: 18 Years to 60 Years ·
Sex: All (male and female)
· Illinois: Evanston
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Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
NCT07181109 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Illinois: Arlington Heights, Chicago, Hazel Crest, Oak Brook
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bpMedManage: Digital Technology to Support Adherence to Hypertension Medications
NCT06307574 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 60 Years and older ·
Sex: All (male and female)
· Illinois: Champaign