Clinical trials recruiting for Liver Metastases

Phase breakdown

Drugs and treatments being studied

Where trials are recruiting (top US states)

Top cities

Self-screener

Recruiting trials

• A Study of Single Fraction Stereotactic Body Radiation Therapy (SBRT) Guided by Magnetic Resonance Imaging (MRI) in People With Liver Metastasis From Colorectal Cancer
  NCT06130280 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 7 locations
• BreCLIM-2 - A RCT Investigating Local Treatment for Breast Cancer Liver Metastases
  NCT04079049 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• COLLISION RELAPSE Trial
  NCT05861505 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases
  NCT04687631 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Cryoablation Combined with Sintilimab Plus Regorafenib in Previously Treated Colorectal Cancer Liver Metastasis
  NCT05057052 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM
  NCT06630624 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• French Assessment of MRD by Liquid Biopsies in Colorectal With Liver Metastasis Patients (FRENCH.MRD.CRLM)
  NCT06287723 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis
  NCT07281924 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Histotripsy Plus Chemotherapy vs Chemotherapy Alone for Advanced Colorectal Liver Metastasis
  NCT07044362 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Improved Recovery by Iron Following Surgery With Blood Loss, the IRIS-trial
  NCT05744219 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Incremental Value of Magnetic Resonance Imaging in Selection of Pancreatic Cancer Patients for Surgery
  NCT05428358 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 99 Years · Sex: All (male and female) · 3 locations
• Liver Transplantation Compared to Chemotherapy in Patients With ColoRectal Cancer
  NCT03494946 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Liver Transplantation in Patients With Unresectable Colorectal Liver Metastases
  NCT04616495 · Phase: Not specified · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases
  NCT03488953 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 2 locations
• Living Donor Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases
  NCT02864485 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 68 Years · Sex: All (male and female) · 1 location
• Neoadjuvant Dupilumab and Toripalimab in MSS CRC Subjects With Resectable Liver Metastases
  NCT07277322 · Phase: Phase 1, Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients
  NCT06280495 · Phase: Phase 2, Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Neoantigen Dendritic Cell Vaccine and Nivolumab in HCC and Liver Metastases From CRC
  NCT04912765 · Phase: Phase 2 · Ages: 21 Years and older · Sex: All (male and female) · 1 location
• PHP in Combination With IPI1/NIVO3 Compared to IPI3/NIVO1 Only in Patients With Uveal Melanoma Liver Metastases
  NCT06519266 · Phase: Phase 3 · Ages: 18 Years and older · Sex: All (male and female) · 6 locations
• Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases
  NCT06300463 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• PrOspEctive Metastases Imaging (POEM)
  NCT07781306 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Promoting Immunotherapy Efficacy With Low-Dose Liver RT
  NCT07225036 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• SBRT + PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases
  NCT06794086 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases
  NCT06200831 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Stereotactic Body Radiation Therapy (SBRT) for Unresectable Liver Metastases
  NCT02185443 · Phase: Phase 2 · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• Stereotactic Magnetic Resonance Guided Radiation Therapy
  NCT04115254 · Phase: Not applicable (e.g. observational or device study) · Ages: 18 Years and older · Sex: All (male and female) · 4 locations
• Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases
  NCT05588388 · Phase: Phase 2 · Ages: No age limits stated · Sex: All (male and female) · 3 locations
• Surgical or Medical Treatment of Breast Cancer Metastasis: A Multicentre Observational Study
  NCT06093022 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 1 location
• The MOMENTUM Study: The Multiple Outcome Evaluation of Radiation Therapy Using the MR-Linac Study
  NCT04075305 · Phase: Not specified · Ages: 18 Years and older · Sex: All (male and female) · 54 locations
• ctDNA-guided Adjuvant Chemotherapy in Liver Metastasis of Colorectal Cancer
  NCT05815082 · Phase: Phase 3 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location

Related conditions

Trials recruiting for Liver Metastases often also study these conditions. Each links to its own recruiting-trial list.

Common questions

Are these trials free to join?

Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.

How do I know if I am eligible for Liver Metastases trials?

Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.

Is this list complete?

No. For the full list, search ClinicalTrials.gov.