Phase 2 NASH trials recruiting now

All NASH trials, every phase

Other phases for NASH

Phase 2 NASH trials

• A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD
  NCT07527910 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 6 locations
• A Precision Medicine Approach Using Gene Silencing to Treat a Chronic Liver Disease Called Metabolic Dysfunction-Associated Steatohepatitis (MASH) in Adult Participants at Increased Genetic Risk for This Condition
  NCT05519475 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 71 locations
• A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
  NCT06920043 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 30 locations
• A Study of a Thyroid Hormone Receptor Beta Isoform (THRβ) Agonist and an Semicarbazide Sensitive Amine Oxidase (SSAO) Inhibitor, Alone and in Combination, in Adults With Presumed Metabolic Dysfunction-associated Steatohepatitis (MASH)
  NCT07288138 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 64 locations
• A Trial to Evaluate the Efficacy, Safety, PK, and PD of HP515 in Non - Alcoholic Fatty Liver Disease ( NASH/MASH )
  NCT07308548 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• A Trial to Learn if ALN-PNP is Safe and Well Tolerated in Healthy Adults and Adult Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
  NCT05648214 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 6 locations
• Cilostazol in the Treatment of Nonalcoholic Fatty Liver Disease
  NCT07238985 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Digoxin In NASH (CODIN)
  NCT06588699 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 2 locations
• Dihydroartemisinin for MAFLD
  NCT07679542 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 45 Years · Sex: All (male and female) · 1 location
• Effect of CoQ10 on the Outcome of MAFLD Patients
  NCT05984745 · Phase: Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 1 location
• Effect of the Combined Application of Cynara Scolymus, Silybum Marianum, Curcuma Longa, and Glycyrrhiza Glabra in Improving Metabolic Associated Fatty Liver Disease : a Randomized Clinical Trial
  NCT06798948 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 2 locations
• Efficacy and Safety of Recombinant Human FGF21-Fc Fusion Protein for Injection (TQA2225/AP025) in Adult Subjects With Non-alcoholic Steatohepatitis (NASH)
  NCT06569524 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 53 locations
• Erdosteine in the Treatment of Nonalcoholic Fatty Liver Disease
  NCT07242222 · Phase: Phase 1, Phase 2 · Ages: 18 Years to 60 Years · Sex: All (male and female) · 1 location
• Evaluating the Safety and Efficacy of Carbocisteine in the Treatment of Nonalcoholic Fatty Liver Disease Patients
  NCT06863376 · Phase: Phase 2 · Ages: 18 Years to 65 Years · Sex: All (male and female) · 1 location
• HuHuangLianzonggan Capsule in Subjects With Nonalcoholic Steatohepatitis: a Phase 2 tRial(HHL-HEPAR)
  NCT05632861 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 20 locations
• Impact of Soymilk on Liver Disease Severity of Children With Non-alcoholic Fatty Liver Disease (NAFLD)
  NCT06133101 · Phase: Phase 2 · Ages: 5 Years to 12 Years · Sex: All (male and female) · 1 location
• Implementing Food Referrals for Equity and Sustained Health
  NCT06661538 · Phase: Phase 2 · Ages: 5 Years and older · Sex: All (male and female) · 2 locations
• Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial
  NCT07193927 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States
  NCT05832229 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 13 locations
• Low-Dose Pioglitazone in Patients With NASH (AIM 2)
  NCT04501406 · Phase: Phase 2 · Ages: 21 Years to 75 Years · Sex: All (male and female) · 2 locations
• Mechanisms of SGLT2 Inhibition in Pediatric Steatotic Liver Disease
  NCT06355310 · Phase: Phase 2 · Ages: 16 Years to 20 Years · Sex: All (male and female) · 1 location
• Milk Thistle Clinical Trial in Pediatric NAFLD
  NCT06477146 · Phase: Phase 2 · Ages: 9 Years to 22 Years · Sex: All (male and female) · 1 location
• Non-Alcoholic Fatty Liver Disease, the HEpatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
  NCT03884075 · Phase: Phase 2 · Ages: 18 Years to 100 Years · Sex: All (male and female) · 1 location
• Phase 2a Study of Safety, Tolerability, and Efficacy of TLC-2716 in Subjects With Hypertriglyceridemia and NAFLD
  NCT06564584 · Phase: Phase 2 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 4 locations
• Randomized Double Blinded Placebo-Controlled w/Semaglutide to Prevent Weight Gain After Liver Transplant
  NCT05424003 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Soluble Fibre Supplementation in NAFLD
  NCT05480696 · Phase: Phase 2 · Ages: 8 Years to 17 Years · Sex: All (male and female) · 1 location
• Study of ADI-PEG 20 Versus Placebo in Subjects With NASH
  NCT05842512 · Phase: Phase 2 · Ages: 18 Years to 80 Years · Sex: All (male and female) · 10 locations
• Study of the Efficacy and Safety of Nicotinamide in Patients With Liver Fibrosis (NICOFIB)
  NCT06599918 · Phase: Phase 2 · Ages: 18 Years to 85 Years · Sex: All (male and female) · 2 locations
• Synbiotics and Fecal Microbiota Transplantation to Treat Non-Alcoholic Steatohepatitis
  NCT05821010 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Tesamorelin for Reduction of Liver Fat in Adults With Fatty Liver Disease (Mock Study)
  NCT07481734 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Thyroid Hormone for Treatment of Nonalcoholic Steatohepatitis in Veterans
  NCT05526144 · Phase: Phase 2 · Ages: 18 Years to 75 Years · Sex: All (male and female) · 1 location
• Trial of CS060380 Tablets for Non-alcoholic Steatohepatitis (NASH)
  NCT07198386 · Phase: Phase 2 · Ages: 18 Years to 70 Years · Sex: All (male and female) · 8 locations

Common questions

What does Phase 2 mean?

See how clinical trials work.

Is this list complete?

No. For the full record, search ClinicalTrials.gov.