Clinical trials recruiting for PIK3CA Mutation
3
Recruiting trials
28
US states with sites
24
Countries
0%
Accept healthy volunteers
Phase breakdown
Phase 1 2Phase 3 1
Drugs and treatments being studied
| Intervention | Trials |
|---|---|
| Fulvestrant | 2 |
| Capivasertib | 1 |
| PF-07220060 100mg | 1 |
| PF-07220060 300 mg | 1 |
| Palbociclib 125mg | 1 |
| RGT-490 | 1 |
| RLY-2608 | 1 |
| Ribociclib 400mg | 1 |
| Ribociclib 600mg | 1 |
| Zovegalisib | 1 |
Where trials are recruiting (top US states)
| State | Recruiting trials |
|---|---|
| California | 3 |
| Texas | 3 |
| Virginia | 3 |
| Arizona | 2 |
| Colorado | 2 |
| Connecticut | 2 |
| Florida | 2 |
| Illinois | 2 |
| Indiana | 2 |
| Massachusetts | 2 |
| Michigan | 2 |
| Missouri | 2 |
Top cities
Fairfax, Virginia 3Houston, Texas 3Ann Arbor, Michigan 2Boston, Massachusetts 2Chicago, Illinois 2Dallas, Texas 2Indianapolis, Indiana 2Los Angeles, California 2Madison, Wisconsin 2Nashville, Tennessee 2
Self-screener
Recruiting trials
- First-in-Human Study of Mutant-selective PI3Kα Inhibitor, RLY-2608, as a Single Agent in Patients With Advanced Solid Tumors and in Combination With Endocrine Therapy +/- a CDK4/6 or CDK4 Inhibitor in Patients With Advanced Solid Tumors or Advanced Breast Cancer
- Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
- Study of RGT-490 in Patients With PIK3CA-Mutated Advanced Solid Tumors
Related conditions
Trials recruiting for PIK3CA Mutation often also study these conditions. Each links to its own recruiting-trial list.
HER2- Negative Breast Cancer 57Breast cancer 2239Advanced Breast Cancer 61Unresectable Solid Tumor 5Metastatic breast cancer 131Hormone Receptor Positive Tumor 10Solid Tumor, Adult 38Ovarian cancer 118Endometrial cancer 68Cervical cancer 71
Common questions
Are these trials free to join?
Study-related care in a clinical trial is usually provided at no cost to participants, and some trials reimburse travel. Costs vary by study - the trial team will explain what is and is not covered. Confirm this directly with them.
How do I know if I am eligible for PIK3CA Mutation trials?
Each trial lists inclusion and exclusion criteria. The screener above checks stated age and sex only. The full eligibility (your medical history, current medications, test results) is assessed by the study team. Open any trial to read its criteria, then contact the site.
Is this list complete?
No. For the full list, search ClinicalTrials.gov.