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A 16-week Trial to Investigate the Efficacy and Safety of Delgocitinib Cream 20 mg/g in Adult Participants With Mild to Severe Palmoplantar Pustulosis
NCT07013201 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Fountain Valley
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A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis
NCT07250802 ·
Phase: Phase 3 ·
Ages: 4 Years to 17 Years ·
Sex: All (male and female)
· California: Chula Vista, Fountain Valley
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A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis
NCT03987763 ·
Phase: Phase 4 ·
Ages: 6 Years to 17 Years ·
Sex: All (male and female)
· California: Fountain Valley, Thousand Oaks
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A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have Not Taken Biologic Medicines
NCT06671483 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Fountain Valley, La Mesa, Thousand Oaks, Tujunga
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A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines
NCT06671496 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Covina
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A Study to Assess Deucravacitinib Safety in Pregnancy
NCT07017699 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: Female
· California: La Jolla
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A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)
NCT06888193 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: Female
· California: Santa Monica
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A Study to Evaluate D-2570 in Participants With Moderate to Severe Plaque Psoriasis
NCT07489885 ·
Phase: Phase 2 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· California: Chula Vista, Fountain Valley, Fremont, Los Angeles
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A Study to Evaluate the Efficacy and Safety of Bimekizumab in Study Participants With Palmoplantar Pustulosis
NCT07219420 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Fremont
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A Study to Evaluate the Efficacy and Safety of JNJ-88545223 for the Treatment of Participants With Active Psoriatic Arthritis
NCT07321873 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Huntington Beach, San Diego
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A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
NCT06979453 ·
Phase: Phase 3 ·
Ages: 12 Years to 17 Years ·
Sex: All (male and female)
· California: Fountain Valley, Fremont, Los Angeles, Northridge
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A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)
NCT06864026 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Apple Valley, Covina, Huntington Beach, La Mesa
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A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)
NCT06857942 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Fountain Valley, Fremont, Los Angeles, Northridge
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A Study to Learn if Bimekizumab Given in Different Ways is Safe and Moves Similarly Throughout the Body Over Time in Adults
NCT07290036 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Apple Valley, Covina, Fullerton, Riverside
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An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis
NCT07449702 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Fountain Valley, Los Angeles, San Diego, Santa Ana
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Continuation Study of Zasocitinib in Adults With Psoriatic Arthritis
NCT07286058 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Fountain Valley, La Mesa, Thousand Oaks
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Correction of Psoriatic T Cell Signatures by Deucravacitinib
NCT05858645 ·
Phase: Phase 4 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: San Francisco
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Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis
NCT07474792 ·
Phase: Phase 2 ·
Ages: 18 Years to 79 Years ·
Sex: All (male and female)
· California: Fountain Valley, Los Angeles, San Diego, Santa Ana
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Elucidating Shared Mechanisms Contributing to NAFLD and PsA Disease Severity With Guselkumab Therapy
NCT06586281 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: No age limits stated ·
Sex: All (male and female)
· California: San Diego
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Evaluate the Safety and Pharmacokinetics/Pharmacodynamics of HS-20118
NCT06846710 ·
Phase: Phase 1 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· California: Anaheim
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Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFα Inadequate Response
NCT06641089 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: La Jolla, Pomona, San Diego, Santa Monica
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Immune Spatial Features of Guselkumab Cutaneous Response
NCT05858632 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
NCT07116967 ·
Phase: Phase 3 ·
Ages: 40 Years and older ·
Sex: All (male and female)
· California: Encinitas, Encino, Fountain Valley, Fremont
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Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
NCT02418442 ·
Phase: Not specified ·
Ages: Up to 21 Years ·
Sex: All (male and female)
· California: Los Angeles, Palo Alto, San Diego, San Francisco
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Open Label Study to Investigate the Safety and Efficacy of Ponesimod in Moderate-to-Severe Chronic Plaque Psoriasis
NCT07362017 ·
Phase: Phase 3 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· California: Fremont
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Psoriatic Immune Response to Tildrakizumab
NCT05390515 ·
Phase: Phase 4 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· California: San Francisco
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Stelara and Tremfya Pregnancy Exposure Registry OTIS Autoimmune Diseases in Pregnancy Project
NCT02103361 ·
Phase: Not specified ·
Ages: No age limits stated ·
Sex: Female
· California: La Jolla
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Study of Targeted Therapies for the Treatment of Adult Participants With Active Psoriatic Arthritis
NCT06865105 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Huntington Beach
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Study to Evaluate Tulisokibart in Adults With Psoriatic Arthritis (MK-7240-015)
NCT07486960 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· California: Riverside, Thousand Oaks, Tujunga
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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
NCT03816345 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Palo Alto, Sacramento
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The Effects of Audio-Based Therapy on Anxiety in Psoriasis
NCT07390487 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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The Impact of Salt Intake on Sodium in the Skin and Inflammatory Skin Disease
NCT07487831 ·
Phase: Phase 4 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: San Francisco
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Use of Total-Body PET to Quantify Systemic and Cutaneous Inflammation in Psoriasis Patients Before and After Intervention With a Nutritionally Balanced Diet
NCT06574178 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· California: Sacramento