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A Biospecimen Collection Study to Identify the Targets of Disease-Reactive T Cells in Patients With Autoimmune Disease
NCT06587828 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Bellaire
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A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)
NCT06764615 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Tyler
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A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
NCT07185009 ·
Phase: Phase 3 ·
Ages: 16 Years to 80 Years ·
Sex: All (male and female)
· Texas: Lubbock, San Antonio, Southlake, Tyler
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A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
NCT04844606 ·
Phase: Phase 3 ·
Ages: 2 Years to 19 Years ·
Sex: All (male and female)
· Texas: Fort Worth
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A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease
NCT07483073 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Kingwood, San Antonio
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A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease
NCT07113522 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Dallas, Garland, Georgetown, Houston
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A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis
NCT07196748 ·
Phase: Phase 3 ·
Ages: 12 Years and older ·
Sex: All (male and female)
· Texas: Austin, Carrollton, Houston, San Antonio
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A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
NCT05076175 ·
Phase: Phase 2, Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· Texas: Fort Worth, Houston
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A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
NCT06598943 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Baytown, Edinburg, Houston, San Antonio
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A Study of JNJ-78934804 in Participants With Moderately to Severely Active Ulcerative Colitis
NCT07577856 ·
Phase: Phase 3 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: San Antonio, Tyler
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A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis
NCT07012395 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Cedar Park, Garland, San Antonio, Southlake
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A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
NCT06095128 ·
Phase: Phase 4 ·
Ages: 18 Years to 65 Years ·
Sex: All (male and female)
· Texas: Dallas, Houston, Mansfield, San Antonio
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A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting
NCT06581328 ·
Phase: Phase 4 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: El Paso, Georgetown, Houston, Katy
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A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
NCT05442567 ·
Phase: Phase 3 ·
Ages: 2 Years and older ·
Sex: All (male and female)
· Texas: Houston
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A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06588855 ·
Phase: Phase 3 ·
Ages: 16 Years to 80 Years ·
Sex: All (male and female)
· Texas: Galveston, Garland, Georgetown, Harlingen
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A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis
NCT04372108 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
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A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis
NCT05287126 ·
Phase: Phase 2 ·
Ages: 12 Years to 17 Years ·
Sex: All (male and female)
· Texas: Abilene
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A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis
NCT06867094 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Katy, Lubbock, Southlake
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A Study to Investigate the Efficacy and Safety of SAR442970 in Adult Participants With Ulcerative Colitis
NCT06975722 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Houston
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A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis
NCT07071519 ·
Phase: Phase 3 ·
Ages: 2 Years to 17 Years ·
Sex: All (male and female)
· Texas: Dallas
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A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis
NCT06636656 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Cedar Park, Houston
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An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Ulcerative Colitis
NCT07184996 ·
Phase: Phase 3 ·
Ages: 16 Years to 80 Years ·
Sex: All (male and female)
· Texas: Baytown, Dallas, Harlingen, Kingwood
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An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis
NCT06398626 ·
Phase: Not specified ·
Ages: 18 Years to 64 Years ·
Sex: All (male and female)
· Texas: Houston, San Antonio, Southlake
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BOOM-IBD2 Pivotal Clinical Trial
NCT06571669 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years to 85 Years ·
Sex: All (male and female)
· Texas: Amarillo, Waco, Wichita Falls
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Confirmatory Clinical Study in Active Ulcerative Colitis
NCT07296315 ·
Phase: Phase 2 ·
Ages: 16 Years and older ·
Sex: All (male and female)
· Texas: San Antonio
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Evaluation the Safety and Efficacy of Lyophilized Fecal Microbiota Transplantation Administered Orally for Prevention of Relapse or Intestinal Inflammation in Adults With Ulcerative Colitis
NCT04373473 ·
Phase: Phase 2 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
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Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
NCT06651281 ·
Phase: Phase 3 ·
Ages: No age limits stated ·
Sex: All (male and female)
· Texas: Garland, Lubbock, San Antonio, Southlake
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LY4268989 (MORF-057) Co-Administered With Mirikizumab in Adults With Moderately to Severely Active Ulcerative Colitis:
NCT07186101 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Cedar Park, Dallas, Fort Worth, Garland
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LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
NCT07415044 ·
Phase: Phase 2 ·
Ages: 18 Years to 80 Years ·
Sex: All (male and female)
· Texas: Fort Worth, Garland, Houston, Mansfield
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Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
NCT06937086 ·
Phase: Phase 3 ·
Ages: 18 Years to 70 Years ·
Sex: All (male and female)
· Texas: San Antonio, Tyler
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Mirikizumab Real World Protocol
NCT06696014 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: San Antonio
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Registry and Biorepository for IBD in Central Texas
NCT04617184 ·
Phase: Not specified ·
Ages: 18 Years to 100 Years ·
Sex: All (male and female)
· Texas: Austin
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Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis
NCT07697456 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Bellaire, Georgetown, Houston, San Antonio
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Study of Tilpisertib Fosmecarbil in Participants With Moderately to Severely Active Ulcerative Colitis
NCT06029972 ·
Phase: Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Boerne, El Paso, Garland, Houston
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Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
NCT06619990 ·
Phase: Phase 1, Phase 2 ·
Ages: 18 Years to 75 Years ·
Sex: All (male and female)
· Texas: Cedar Park, Denton, Garland, Georgetown
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Study to Evaluate the Fecal Microbiota Transplantation (FMT) in the Treatment of Ulcerative Colitis
NCT05786404 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
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Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO
NCT03816345 ·
Phase: Phase 1 ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Fort Worth, Houston, Richardson
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Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
NCT04751396 ·
Phase: Not specified ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Houston
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Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission
NCT05230173 ·
Phase: Not applicable (e.g. observational or device study) ·
Ages: 18 Years and older ·
Sex: All (male and female)
· Texas: Dallas, Houston