Boston Early-Onset Chronic Obstructive Pulmonary Disease (COPD) Study
Recruiting · NCT01177618 · Observational (researchers observe without assigning treatment) · Lead sponsor: Brigham and Women's Hospital
View the official record on ClinicalTrials.gov →What this trial is about
Chronic obstructive pulmonary disease (COPD) is often caused by cigarette smoking, but genetic predisposition also influences COPD susceptibility. The purpose of this study is to identify genetic factors that predispose some individuals to develop COPD.
Who can take part
Age range
No age limits stated
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- for Early-Onset COPD Probands:
- Early onset of COPD in individuals younger than 53 years old
- Spirometry results that are indicative of severe COPD (FEV1 \< 40% predicted)
- Physician-diagnosed COPD
Exclusion criteria
- for Early-Onset COPD Probands:
- Severe alpha-1 antitrypsin deficiency
- Other chronic lung diseases in participants with COPD (except asthma)
- Pregnant
- Any previous lung surgery including lung transplant or lung reduction volume surgery (LVRS); unless prior Pulmonary Function Tests are available
Where it is running
1 location listed across 1 US state.
- Brigham and Women's Hospital - Boston, Massachusetts, United States