Epidemiology of Inflammatory Bowel Disease in the Songpa-Kangdong District, Seoul, Korea.
Recruiting · NCT01731665 · Observational (researchers observe without assigning treatment) · Lead sponsor: Asan Medical Center
View the official record on ClinicalTrials.gov →What this trial is about
The purpose of this study is to evaluate the incidence, prevalence, clinical characteristics and prognosis of Crohn's disease and ulcerative colitis over time in a district of Seoul, Korea.
Who can take part
Age range
No age limits stated
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Definite cases of CD and UC
- Patients are diagnosed with CD if they meet at least 2 of the following criteria:
- clinical history of abdominal pain, weight loss, malaise, diarrhea, and/or rectal bleeding
- endoscopic findings of mucosal cobblestoning, linear ulceration, skip areas, or perianal disease
- radiologic findings of stricture, fistula, mucosal cobblestoning, or ulceration
- macroscopic appearance of bowel wall induration, mesenteric lymphadenopathy, and "creeping fat" at laparotomy
- pathologic findings of transmural inflammation and/or epithelioid granulomas
- nly patients who meet these criteria for at least 2 months are included.
- Patients are diagnosed with UC only if all 3 of the following criteria are present
- a typical history of diarrhea or blood and pus or both in the stool for longer than 4 weeks
- a typical sigmoidoscopic or colonoscopic picture with diffusely granular, friable, or ulcerated mucosa without rectal sparing or skip lesions or radiological signs of characteristic continuous granular or ulcerated mucosa
- characteristic histopathological signs of inflammation on biopsy
Exclusion criteria
- IBD unclassified
- Ethnic groups other than Korean
Where it is running
2 locations listed.
- Asan Medical Center - Seoul, South Korea
- Asan Medical Center - Seoul, South Korea