Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.
Recruiting · NCT01998750 · Observational (researchers observe without assigning treatment) · Lead sponsor: Columbia University
View the official record on ClinicalTrials.gov →What this trial is about
This study aims to investigate genetic causes of early childhood obesity. The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood to perform genetic testing from the participants and invite family members to enroll in the study.
Who can take part
Age range
Up to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- \- BMI \> 99th percentile documented at age \< 6 years of age
Exclusion criteria
- Known genetic causes of obesity
- Known Endocrine causes of obesity.
- Neurologic tumor, trauma or surgery
- Prior malignancy or transplant
- Known autoimmune diseases
- Edema of a known or unknown cause
- Prolonged steroid use.
Where it is running
2 locations listed across 2 US states.
- Boston Children's Hospital - Boston, Massachusetts, United States
- Columbia University Medical Center - New York, New York, United States