Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer
Recruiting · NCT02014389 · Observational (researchers observe without assigning treatment)
View the official record on ClinicalTrials.gov →What this trial is about
Objective perimetry can better monitor visual field defects in retinal dystrophy and Glaucoma patients than conventional subjective perimetry. The PLR ( Pupil Light Reflex to short and long wavelength stimuli should be significantly lower compared to healthy participants in areas of visual field defects in retinal dystrophy and Glaucoma patients.
Who can take part
Age range
18 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Age 18-80 years old.
- Signing informed consent.
- Pupillary reflex to light.
Exclusion criteria
- Cloudy corneas.
- Surgical intraocular ophthalmic procedure within the past 30 days.
- No reactive pupils.
- Synechia of the iris to the lens after surgery or inflammation.
- Neovascularization.
- Axenfeld-Rieger Syndrome.
- Iris atrophy (ICE syndrome).
- Iris coloboma.
- Sphincter damage due to ischemia.
- Sphincter damage due to trauma (tears of sphincter or diffuse damage to muscle).
- Sphincter damage due to Herpes Zoster Uveitis.
- Sphincter damage due to high intraocular pressure.
- Iris tumor or cyst.
- Ectropion uvae.
- Adie's pupil.
- Third nerve aberrant regeneration of the iris sphincter.
- RP patients with Optic neuropathy with the potential of producing a positive RAPD (Relative Afferent Pupillary Defect).
- Chronic use of myotics or mydriatics.
- Systemic medication that have affect on pupillary reflex .
- Any condition preventing accurate measurement or examination of the pupil.
Where it is running
1 location listed.
- Sheba Medical Center - Tel Litwinsky, Israel