Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
Recruiting · NCT02222844 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
Preoperative MRI scan
What this trial is about
Patients with suspected or proven sigmoid colon adenocarcinoma, eligible for curative treatment whose MRI can be reviewed prior to surgery and has no decision regarding radical treatment are eligible. Patient are randomised to the control arm which the standard care of preoperative CT imaging and subsequent discussion by the Multidisciplinary Team or the interventional arm which has the additional use of MRI imaging and subsequent discussion by the Multidisciplinary Team. Patients are followed up at 1 and 3 years together with QoL questionnaires.
Who can take part
Age range
16 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Have a suspected or proven sigmoid colon adenocarcinoma
- Is eligible for curative treatment
- Has no irresectable metastatic disease
- MRI can be reviewed by an MDT prior to surgery
- Has no decision regarding radical treatment
- Have provided written informed consent to participate in the study
- Be aged 16 years or over
Exclusion criteria
- Have metastatic disease (including resectable liver metastases)
- Have a synchronous second malignancy
- Are contraindicated for MRI
- Are contraindicated for or have allergy to Buscopan (e.g. glaucoma, small or large bowel obstruction, GFR\<30)
- Have severe co-morbidities or previous medical history that prevent the application of eventual chemo/radiotherapy
Where it is running
16 locations listed.
- Hinchingbrooke Hospital - Huntingdon, Cambridgeshire, United Kingdom
- Leighton Hospital - Crewe, Cheshire, United Kingdom
- University Hospital of North Tees - Stockton-on-Tees, County Durham, United Kingdom
- Croydon University Hospital - Thornton Heath, Croydon, United Kingdom
- Chesterfield Royal - Chesterfield, Derbyshire, United Kingdom
- Queen Alexandra Hospital - Portsmouth, Hampshire, United Kingdom
- St Mark's Hospital - Middlesex, Harrow, United Kingdom
- Maidstone Hospital - Maidstone, Kent, United Kingdom
- Queen Elizabeth the Queen Mother Hospital - Margate, Kent, United Kingdom
- North Manchester General Hospital - Crumpsall, Manchester, United Kingdom
- University Hospital of South Manchester & Manchester Royal Infirmary - Wythenshawe, Manchester, United Kingdom
- Harrogate District Hospital - Harrogate, North Yorkshire, United Kingdom
- Musgrove Park Hospital - Taunton, Somerset, United Kingdom
- Yeovil District Hospital - Yeovil, Somerset, United Kingdom
- Royal Marsden Hospital - Sutton, Surrey, United Kingdom
- Salisbury District Hospital - Salisbury, Whiltshire, United Kingdom