Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome
Recruiting · NCT02602769 · Observational (researchers observe without assigning treatment) · Lead sponsor: Columbia University
View the official record on ClinicalTrials.gov →Interventions studied
Transcriptome profiling
What this trial is about
Rapid onset Obesity, Hypoventilation, Hypothalamic dysfunction and Autonomic Dysregulation (ROHHAD) is a syndrome named in 2007. The hallmark of the syndrome is the rapid onset obesity and dysregulation of central ventilation. There is little information about the metabolic changes that lead to the rapid onset obesity in these children. The investigators would like to study the metabolic phenotype of these children to understand the disturbances in energy balance that lead to the rapid onset obesity.
Who can take part
Age range
2 Years to 20 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Children with ROHHAD syndrome
Exclusion criteria
- Children with known genetic causes of obesity
Where it is running
2 locations listed across 1 US state.
- Boston Children's Hospital - Boston, New York, United States
- Columbia University Irving Medical Center - New York, New York, United States