Taste Physiology in Obese Volunteers Before and After Bariatric Surgery
Recruiting · NCT02902198 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery. Intragastric administration of glucose, monosodium glutamate, chloroquine and placebo is followed by functional brain MRI in obese humans before and 3 months after surgery.
Who can take part
Age range
18 Years to 55 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- morbidly obese patients (BMI min 35kg/m2) scheduled for bariatric surgery
- right handed
Exclusion criteria
- cardiovascular disease
- neurologic/psychiatric disorders
Where it is running
1 location listed.
- University Hopital Basel - Basel, Switzerland