Prospective Investigation of Multiple Sclerosis in the Three Rivers Region
Recruiting · NCT02994121 · Observational (researchers observe without assigning treatment) · Lead sponsor: University of Pittsburgh
View the official record on ClinicalTrials.gov →What this trial is about
In this longitudinal prospective natural history study of multiple sclerosis (MS), the overarching goal is to understand the factors that influence individual variation in disease trajectory and treatment response and pave the way for realizing precision medicine in MS. Because MS is a chronic neurological disorder, this observational cohort study will span a 30-year time frame.
Who can take part
Age range
7 Years and older
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Inclusion criteria for MS patients include:
- Age 7 years or older
- Willing and able to provide consent (for \>=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
- Diagnosis of multiple sclerosis or related disorders, including a first central nervous system demyelinating episode with a positive MRI scan or abnormal MRI scans characteristic of MS but no clinical symptoms of the disease
- For healthy controls:
- Age 7 years or older
- Willing and able to provide consent (for \>=18 years) or assent with permission from at least one of the child's parents (for \<18 years)
- No known personal history of multiple sclerosis or related disorders
- No other chronic diseases
- Family members, unrelated household controls, or controls from the general population could be eligible
- There is no
Where it is running
1 location listed across 1 US state.
- University of Pittsburgh - Pittsburgh, Pennsylvania, United States