Early Rheumatoid Arthritis Lung Disease Study
Recruiting · NCT03192267 · Observational (researchers observe without assigning treatment) · Lead sponsor: University of Nebraska
View the official record on ClinicalTrials.gov →What this trial is about
Extra-articular (outside of joints) disease occurs in approximately 50% of rheumatoid arthritis (RA) patients, with the lung being a common site of involvement. The goals of this study are to investigate and characterize lung disease and its prevalence in early RA participants. This will be done through pulmonary function and high resolution chest computed tomography (CT), questionnaires, and serum studies. Another goal is to find novel biomarkers, such anti-malondialdehyde-acetaldehyde (MAA) antibodies, as predictors of lung disease in RA participants.
Who can take part
Age range
19 Years to 90 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- 19-90 years of age
- Able to give informed consent
- Diagnosis of RA by a Rheumatologist using 2010 American College of Rheumatology (ACR) criteria within the past 2 years
Exclusion criteria
- Inflammatory arthritis that does not meet 2010 American College of Rheumatology (ACR) criteria for rheumatoid arthritis (RA)
- Pregnant
Where it is running
1 location listed across 1 US state.
- University of Nebraska Medical Center - Omaha, Nebraska, United States