LVAD Conditioning for Cardiac Recovery
Recruiting · NCT03238690 · Interventional (participants receive a specific treatment) · Lead sponsor: STAVROS G DRAKOS
View the official record on ClinicalTrials.gov →Interventions studied
Controlled Cardiac Reloading through LVAD Speed Adjustment
What this trial is about
The purpose of this study is to investigate the potential recovery of heart function in end-stage heart failure patients supported with a Left Ventricular Assist Device (LVAD) through applying a myocardial conditioning protocol. During myocardial conditioning, LVAD speed is reduced gradually in order to increase the work load of the heart. Multiple previous studies have shown that interventions like this may improve heart function and give patients the opportunity for a better quality of life.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Diagnosed with heart failure undergoing LVAD implantation as a bridge to transplant
- Enrolled in the Effects of Mechanical Unloading on Myocardial Function and Structure study (IRB 30622)
Exclusion criteria
- Neither the subject nor the subject's representative is willing to provide written consent for participation
- Subjects with adverse events leading to hospitalization during the optimum unloading phase are excluded from participation in the controlled reloading phase
Where it is running
1 location listed across 1 US state.
- University of Utah - Salt Lake City, Utah, United States