The GEOLynch Cohort Study
Recruiting · NCT03303833 · Observational (researchers observe without assigning treatment) · Lead sponsor: Wageningen University
View the official record on ClinicalTrials.gov →Interventions studied
No intervention, observational study.
What this trial is about
The GEOLynch cohort study has been established to investigate the influence of genetic, environmental and other factors on tumour risk in persons with Lynch syndrome.
Who can take part
Age range
18 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Persons with a known mutation in a gene that causes Lynch syndrome, i.e. with an inherited monoallelic pathogenic germline mutation in either the MLH1, MSH2, MSH6, PMS2 or EPCAM gene.
- Aged between 18 and 80 years at inclusion.
Exclusion criteria
- Additional carrier of another hereditary colon cancer predisposition syndrome (e.g. FAP)
- (Chronic) Inflammatory bowel disease
- Non-Dutch speaking
- Dementia or another mental condition that makes it impossible to fill out questionnaires
- Terminally ill persons
Where it is running
1 location listed.
- Wageningen University - Wageningen, Netherlands