Berlin-Brandenburg Pregnancy Cohort
Recruiting · NCT03313024 · Observational (researchers observe without assigning treatment) · Lead sponsor: Charite University, Berlin, Germany
View the official record on ClinicalTrials.gov →What this trial is about
This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.
Who can take part
Age range
18 Years to 45 Years
Sex
Female
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- healthy pregnant women after giving informed consent
- pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes
Exclusion criteria
- infections
- alcohol and drug abuse
- manifest and chronic diseases
Where it is running
1 location listed.
- Experimental and Clinical Research Center (ECRC) - Berlin, Germany