Bariatric Surgery and Pharmacokinetics of Quetiapine
Recruiting · NCT03449472 · Observational (researchers observe without assigning treatment) · Lead sponsor: Norwegian University of Science and Technology
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on quetiapine are investigated.
Who can take part
Age range
18 Years to 70 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
- Being a Norwegian citizen
Exclusion criteria
- Having previously undergone resections in the GI-tract
Where it is running
1 location listed.
- St. Olavs University Hospital - Trondheim, Norway