Enhancing Renal Graft Function During Donor Anesthesia
Recruiting · NCT03778944 · Interventional (participants receive a specific treatment) · Lead sponsor: Nazmy Edward Seif
View the official record on ClinicalTrials.gov →Interventions studied
Adequate hydrationDopamine infusionMannitol infusion
What this trial is about
Renal transplantation is now recognized as the treatment of choice for patients with end-stage renal disease. An optimum anesthetic regimen should enhance the function and perfusion of the transplanted kidney. The aim of this study is to assess \& compare the effectiveness of 3 different modalities in this respect: Mannitol, Dopamine and adequate hydration.
Who can take part
Age range
18 Years to 60 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- end-stage renal disease, for living-donor kidney transplantation
Exclusion criteria
- severe cardiac or hepatic dysfunction
- coagulopathy
Where it is running
1 location listed.
- Kasr Al-Ainy Hospital, Cairo University - Cairo, Egypt