Sex-Specific Effects of Endocrine Disruption on Aging and Alzheimer's Disease
Recruiting · NCT03821857 · Interventional (participants receive a specific treatment) · Lead sponsor: Mayo Clinic
View the official record on ClinicalTrials.gov →Interventions studied
18-F-Flortaucipir
What this trial is about
The researchers are trying to determine whether ovarian hormones are associated with aging processes and with the risk of developing Alzheimer's disease in women.
Who can take part
Age range
60 Years and older
Sex
Female
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Phase 4
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Women who previously participated in this study
- Currently aged 60 years and older
- More than six months post chemotherapy or major surgery requiring general anesthesia
- Willing and able to sign informed consent
Exclusion criteria
- Not able to read and speak English
- In hospice
- Claustrophobic
- If undergoing Tau imaging, cannot have QT Prolongation
- Mayo Clinic Jacksonville-
- Inclusion Criteria:
- African American Women
- Currently aged 60 years and older
- More than six months post chemotherapy or major surgery requiring general anesthesia
- Willing and able to sign informed consent
- Exclusion Criteria:
- Not able to read and speak English
- In hospice
- Claustrophobic
- If undergoing Tau imaging, cannot have QT Prolongation
Where it is running
2 locations listed across 2 US states.
- Mayo Clinic - Jacksonville, Florida, United States
- Mayo Clinic - Rochester, Minnesota, United States