Change of Adipose Tissues and Triglyceride After Bariatric Surgery or Life-style Intervention
Recruiting · NCT03875625 · Interventional (participants receive a specific treatment) · Lead sponsor: Chinese University of Hong Kong
View the official record on ClinicalTrials.gov →Interventions studied
Bariatric surgeryConventional care (control)Dietitian led life style modification intervention
What this trial is about
The study is aimed * To quantify the change of adipose tissues, triglyceride in liver and pancreas and cholesterol after lifestyle intervention or bariatric surgery. * To test the hypothesis that Brown fat is an independent biomarker for the development of Non Alcoholic Fat Liver Disease (NAFLD) * To study the association among Brown fat, NAFLD and obesity.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- BMI ≥ 25-30 kg/m2
- BMI ≥ 30 kg/m2 with Metabolic syndrome
- BMI ≥ 35 kg/m2 for morbid obesity
Exclusion criteria
- Other kind of hepatic diseases
- Under medications known to affect liver fat
- Waist circumference ≥ 150 cm
- Weight ≥ 250 kg
- MRI contraindications
Where it is running
2 locations listed.
- The Chinese University of Hong Kong, Prince of Wale Hospital - Hong Kong, Shatin, Hong Kong
- The Chinese University of Hong Kong, Prince of Wale Hospital - Hong Kong, Shatin, Hong Kong