Registry of Subjects at Risk of Pancreatic Cancer
Recruiting · NCT04095195 · Observational (researchers observe without assigning treatment) · Lead sponsor: Associazione Italiana per lo Studio del Pancreas
View the official record on ClinicalTrials.gov →Interventions studied
EndoultrasonographyMRCP
What this trial is about
IRFARPC is a multicenter national registry designed to study the diagnosis and predisposing factors of subjects with an inherited increased risk for pancreatic cancer.
Who can take part
Age range
18 Years to 80 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- to enter the registry:
- individuals with at least two relatives suffering from pancreatic cancer, with at least 1 first-degree and until the third-degree
- subjects with known genetic mutation of BRCA2, BRCA1, p16, PALB2 with at least 1 first- or 2nd-degree relative suffering from pancreatic cancer
- subjects suffering from FAMMM Syndrome
- subjects suffering from Peutz-Jeghers Syndrome
- subjects suffering from PRSS-1- or CFTR- or SPINK-1- related pancreatitis
- subjects suffering from Lynch syndrome with at least 1 first- or 2nd-degree relative suffering from pancreatic cancer
- Inclusion criteria to join the "radiologic follow-up":
- 45 years or 10 years younger than the youngest index case of pancreatic cancer in the family for familial cases
- 40 years or 5 years younger than the youngest index case of pancreatic cancer for subjects suffering from hereditary/genetic pancreatitis, Lynch syndrome, or carrying a known BRCA 1/2, PALB2, p16 genetic mutation with familiarity for pancreatic cancer
- 30 years for subjects suffering from FAMMM, Peutz-Jeghers syndrome
Exclusion criteria
- \- pregnancy
Where it is running
4 locations listed.
- San Raffele Vita Salute University Hospital - Milan, Italy
- Chirurgia Generale e del Pancreas - Verona, Italy
- Istituto Clinico Humanitas - Rozzano, Milan, Italy
- Ospedale Pederzoli - Peschiera del Garda, Verona, Italy