Ovarian Hyperstimulation and Fibrin Clot Properties.
Recruiting · NCT04166825 · Interventional (participants receive a specific treatment) · Lead sponsor: Jagiellonian University
View the official record on ClinicalTrials.gov →Interventions studied
fibrin clot properties
What this trial is about
The impact evaluation of ovarian hyperstimulation on coagulation and fibrinolysis in infertile women. Comparative analysis between different ovarian stimulation protocols on thrombin formation and efficiency of fibrinolysis in women diagnosed with infertility.
Who can take part
Age range
18 Years to 40 Years
Sex
Female
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- infertility defined based on the WHO 2010 criteria
Exclusion criteria
- ovarian involvement
- oral contraceptives use within previous 3 months
- dienogest therapy within 3 months until ART
- thrombotic events in the medical history
- severe hypertension
- diabetes mellitus
- the presence of known VTE risk factors, including obesity, recent major surgery with prolonged immobilization or trauma,
- deficiency of antithrombin, protein C or protein S,
- antiphospholipid syndrome,
- known malignancy,
- any chronic inflammatory diseases (e.g. rheumatoid arthritis)
- advanced chronic renal disease (estimated glomerular filtration rate \[eGFR\] \<30 ml/min),
- international normalized ratio (INR) more than 1.2 at the day of blood draw
- pregnancy.
Where it is running
1 location listed.
- Department of Gynecological Endocrinology Jagiellonian University Medical College - Krakow, Małopolska, Poland