Effects of Left Atrial Appendage Resection and Marshall Ligament Amputation on Clinical Outcome in Patients Undergoing Off-pump Coronary Artery Bypass
Recruiting · NCT04220047 · Interventional (participants receive a specific treatment) · Lead sponsor: China National Center for Cardiovascular Diseases
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Surgical occlusion of the left atrial appendage (LAAO) is sometimes performed during the cardiac surgery to reduce long-term risk of stroke.A previous study found that LAAO may be associated with increased risk of postoperative atrial fibrillation.New-onset atrial fibrillation (NOAF) after coronary artery bypass graft is related to an increased short-term and long term risk of stroke and mortality.Marshall ligament amputation may reduce the occurence of atrial fibrillation. However, little is known whether this approach is justified during the coronary artery bypass graft.Therefore, this study aimed to investigate whether LAAO and Marshall ligament amputation during off-pump coronary artery bypass was associated with reduced risks of postoperative new-onset atrial fibrillation and stroke.
Who can take part
Inclusion criteria
- isolated first off-pump coronary artery bypass
Exclusion criteria
- Preoperative atrial fibrillation or a history of atrial fibrillation;
- Concurrent cardiac or non-cardiac surgery
- Intraoperative convert to bypass bypass surgery
- Emergency surgery
- History of previous cardiac surgery
- Severe organ dysfunction
Where it is running
1 location listed.
- Fuwai Hospital - Beijing, China