COMPuter-assisted Self-training to Improve EXecutive Function
Recruiting · NCT04229056 · Interventional (participants receive a specific treatment) · Lead sponsor: Bispebjerg Hospital
View the official record on ClinicalTrials.gov →Interventions studied
Computer-based cognitive rehabilitation (CBCR)General computer-based cognitive stimulation
What this trial is about
This project explores the effects of specialized computer-based cognitive rehabilitation (CBCR) targeting executive functions in three groups of patients: Stroke, Cardiac Arrest and Parkinson's Disease. The effect of specialized CBCR is compared to generally cognitively stimulating activities on a computer
Who can take part
Age range
18 Years to 100 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- A diagnose of stroke, cardiac arrest or Parkinson's disease.
- Aged 18 years or older.
- Impaired working memory measured with CABPad working memory test, cut off for inclusion: 5 symbols or less backwards
- Computer and internet access at home.
- Providing informed consent.
- Inclusion criteria specific for stroke
- Inclusion within 6 months post-stroke
- Stroke confirmed by clinical findings and imaging, both AIS and ICH is allowed.
- Initial stroke severity \>/= NIHSS 3.
- Inclusion criteria specific for cardiac arrest
- Inclusion within 6 months post ictus.
- Inclusion criteria specific for Parkinson's disease
- Clinical diagnosis of PD.
- Anti-parkinsonian medical treatment (dopaminergic or other).
Exclusion criteria
- Informed consent not provided
- Other neurological or psychiatric disease which is expected to influence the patient's ability to participate in the trial according to the investigator
- Not able to participate according to investigator
- Exclusion criteria specific for stroke
- Patients with massive anosognosia for executive dysfunction or patients with no subjective feeling of executive dysfunction (Patient sustains total denial of executive symptoms over time)
- Patients with severe aphasia, in which it is unclear whether the patient's performance on a neuropsychological test-battery is due to aphasia and not executive dysfunction.
- Exclusion criteria specific for cardiac arrest • None
- Exclusion criteria specific for PD
- Diagnosis of PD Dementia according to the MDS PD Dementia criteria
Where it is running
2 locations listed.
- Bispebjerg Hospital - Copenhagen, Denmark
- Rigshospitalet - Copenhagen, Denmark