Incident Chronic Obstructive pulmoNary dIsease Cohort Study (ICONIC)
Recruiting · NCT04252781 · Interventional (participants receive a specific treatment) · Lead sponsor: Assistance Publique - Hôpitaux de Paris
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
Chronic Obstructive Pulmonary Disease (COPD), , secondary to smoking, is a major public health issue with very high direct and indirect costs. The impact on the health system of undiagnosed patients, up to 70% of patients, is increasingly documented. However, systematic spirometry screening remains controversial among smokers in the absence of data to link the detection of new patients with improved management and clinical events and health goals. More generally, there is little data on the evolution of patients in real life once they have entered the care system. The premise is that with systematic screening in general medicine, it is possible to identify the evolution of newly diagnosed COPD patients, to distinguish the different possible evolutions according to the initial phenotype and the management.
Who can take part
Inclusion criteria
- Inclusion criteria of smokers with spirometry (pre-inclusion)
- Age\> 35 years
- Smoking \> 20 PA
- Active smoking (cessation \< 1 month)
- Signature of consent to participate in Phase I of the study
- Inclusion criteria for patients with incidental COPD
- FEV1 / FVC \<70% of the theoretical value and / or \<LLN (Lower limit of normal)
- Signature of consent to participate in Phase II of the study
Exclusion criteria
- Known COPD
- Cancer being treated
- No affiliation to the social security or other social protection scheme
- Pregnant or lactating woman
- Patient deprived of liberty or under legal protection (under tutorship or curatorship
Where it is running
1 location listed.
- Hopital Henri MONDOR - Créteil, Île-de-France Region, France