Brown Adipose Tissue Activation by Spinal Cord Stimulation
Recruiting · NCT04326192 · Interventional (participants receive a specific treatment) · Lead sponsor: Oregon Health and Science University
View the official record on ClinicalTrials.gov →Interventions studied
Research electrode
What this trial is about
The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.
Who can take part
Age range
21 Years to 70 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Age: 21-70 years
- Persistent neuropathic leg and back pain
- Subjects who are already planning to undergo SCS for pain
- Subjects who have not received a prior SCS trial for pain
- Subjects with a BMI of 25-45, using formula; weight (lb) / \[height (in)\]2 x 703
Exclusion criteria
- Not considering SCS for pain
- Forensic patient
- Taking beta blockers
- Weight change \> 5% within last 3 months
- Habitual tobacco use
- Habitual excessive alcohol use
- Pregnancy
- Decisionally impaired adults
- Children
- Neonates
- Subjects with a BMI of \<25 or \>45
Where it is running
1 location listed across 1 US state.
- Oregon Health & Science University - Portland, Oregon, United States