The Olmsted NAFLD Epidemiology Study (TONES)
Recruiting · NCT04365855 · Interventional (participants receive a specific treatment) · Lead sponsor: Mayo Clinic
View the official record on ClinicalTrials.gov →Interventions studied
Blood drawFibro ScanLiver biopsyMagnetic Resonance Elastography
What this trial is about
Researchers are assessing the prevalence of Non-alcoholic Fatty Liver Disease (NAFLD) and Nonalcoholic Steatohepatitis (NASH) in the population and assembling a well-characterized cohort of adults with NAFLD and NASH to validate models of NAFLD diagnosis and determine long-term outcomes.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Olmsted County residents at the time of search
- Age 18 or older
- No personal history of NAFLD diagnosis (administrative codes)
Exclusion criteria
- Alcohol in excess (more than 20 gm per week in women and 30 gm per week in men)
- Currently pregnant
- Have contraindications to MRI (MRI incompatible implanted devices, severe claustrophobia)
Where it is running
1 location listed across 1 US state.
- Mayo Clinic in Rochester - Rochester, Minnesota, United States