CONFIRM: Magnetic Resonance Guided Radiation Therapy
Recruiting · NCT04368702 · Interventional (participants receive a specific treatment)
View the official record on ClinicalTrials.gov →Interventions studied
Viewray MRIdian® Linac
What this trial is about
This research is being done to determine the safety and feasibility of using a type of radiation guided by magnetic resonance imaging (MRI) and chemotherapy to treat patients with gastric and breast cancer. The name of the radiation machine involved in this study is the MRIdian Linear Accelerator.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Participants must have histologically or cytologically confirmed malignancy requiring radiation
- Age 18 years of older
- ECOG performance status ≤2 (Karnofsky ≥60%, see Appendix A)
- Ability to understand and the willingness to sign a written informed consent document.
- Any further criteria listed in the specific disease site cohort
Exclusion criteria
- History of allergic reactions attributed to gadolinium-based IV contrast
- \-- Note: If patient will not receive contrast, this is not applicable and kidney function will not affect eligibility
- Severe claustrophobia or anxiety
- Participants who cannot undergo an MRI
- Any other exclusion criteria listed in the specific disease site cohort
Where it is running
2 locations listed across 1 US state.
- Brigham & Women's Hospital - Boston, Massachusetts, United States
- Dana Farber Cancer Institute - Boston, Massachusetts, United States