SAMBA Trial: Towards a Paradigm Shift in Severe Asthma Management: Deep Analysis of the Effect of suBmaximal Aerobic Training
Recruiting · NCT04395937 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Liege
View the official record on ClinicalTrials.gov →Interventions studied
Aerobic exercise trainingRespiratory physiotherapy
What this trial is about
The effects of regular exercise on asthma control has not yet been well demonstrated. The aim of this study is to investigate the impact of submaximal aerobic training on exercise tolerance (VO2max - primary outcome) and a set of secondary outcomes: quality of life, asthma symptoms control, bronchial and systemic inflammatory markers, lung function, bronchial hyperresponsiveness, anxiety and depression and body composition in patients with persistant asthma.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- asthmatic patient
- aged 18- 65 years
- ACQ \> 1.5
- stable background treatment comprising at least one inhaled corticosteroid or an anti-leukotriene
Exclusion criteria
- IMC \> 35
- severe osteoarthritis of the knees and hips
- unstable angor
- Severe uncontrolled hypertension
Where it is running
1 location listed.
- Chu Liege - Liège, Liege, Belgium