Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB
Recruiting · NCT04422405 · Interventional (participants receive a specific treatment) · Lead sponsor: Spital Limmattal Schlieren
View the official record on ClinicalTrials.gov →Interventions studied
One Anastomosis Gastric Bypass (OAGB)
What this trial is about
Evaluation of the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass (OAGB)
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- BMI\> 35 kg/m2
- 2 years of controlled conservative obesity treatment without weight reduction
- patients should give their consent to participate in the study
Exclusion criteria
- Less than 2 years of conservative obesity treatment
- cancer
- cirrhosis Child-Pough score A
- Crohn's disease
- serious psychiatric disorder, which led to in-hospital treatment in psychiatric clinic in the past two years
- drug consumption
- non-compliance
- hiatal hernia \> 4cm
- gastric pouch \< 10cm
- Barett esophagus
- erosive esophagitis Grade C or D according to the Los Angeles Classification
- endoscopically proven gastric stricture
- acid exposition time \> 6% (Lyon criteria)
- reflux episodes\> 80 /24 hours (Lyon criteria)
- insufficient low esophageal sphincter according to manometry findings
- pathological findings in the impedance pH-metry (acid and non-acid reflux)
Where it is running
1 location listed.
- Limmattal Hospital - Schlieren, Canton of Zurich, Switzerland