Optical Coherence Tomography Angiography in Subjects With Retinal Vascular Disease
Recruiting · NCT04505618 · Interventional (participants receive a specific treatment) · Lead sponsor: Johns Hopkins University
View the official record on ClinicalTrials.gov →Interventions studied
Axial Length Measurement DeviceFundus ImagingSpectral-Domain (SD) OCT AngiographySwept-Source (SS) OCT Angiography
What this trial is about
This study will perform a prospective, longitudinal analysis of clinical and imaging findings from normal controls and subjects with retinal vascular disease to better define the diagnostic imaging criteria that signify change in disease stage. This includes disease progression in early stages of disease or disease regression with appropriate standard-of-care treatment.
Who can take part
Age range
18 Years to 99 Years
Sex
All (male and female)
Healthy volunteers
Yes - healthy volunteers may be accepted
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Eligibility criteria (as published)
Exclusion Criteria:
* Both subjects with diseases and controls:
* Children (age\<18)
* Pregnant females
* Developmentally delayed subjects
* Subjects unable to provide informed consent
* Inability to cooperate with tests and study instructions
* Images with motion artifact or signal strength \< 7
* History of glaucoma
* History of age-related macular degeneration
* History of any visually significant eye disease
* History of proliferative diabetic retinopathy
* History of any inflammatory disease
* History of heart disease
* History of thyroid disease.
* Additional criteria for controls:
* History of any type of Diabetes Mellitus
* History of any type of Hypertension
Where it is running
1 location listed across 1 US state.
- Wilmer Eye Institute - Baltimore, Maryland, United States