"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
Recruiting · NCT04690972 · Observational (researchers observe without assigning treatment) · Lead sponsor: Institut National de la Santé Et de la Recherche Médicale, France
View the official record on ClinicalTrials.gov →Interventions studied
Blood sample during diagnostic testBlood sample during surgeryTaking an additional biopsy
What this trial is about
Development of preclinical translational models for chronic liver tumors and diseases study, such as spheroids cultured in autologous medium and murine xenograft models to test the efficacy of new therapeutic strategies.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not specified
Study type
Observational (researchers observe without assigning treatment)
Inclusion criteria
- Patients
- diagnosed with chronic liver disease (viral or not)
- diagnosed with at least one liver nodule for which a biopsy is planned as part of the care
- for hepatobiliary surgery planned as part of care
- for locoregional treatment for HCC is indicated
- Patients able to receive and understand information relating to the study and give their written informed consent
- Patients affiliated to the French social security system
Exclusion criteria
- Minor patients
- Patients under legal protection,
- Patients subject to legal protection or unable to express their consent,
- Patients in a situation of social fragility,
- Pregnant or breastfeeding woman,
- No signing of informed consent.
Where it is running
1 location listed.
- PU-PH, Directeur de l'UMR_S1110 Unité Inserm d'affiliation : UMR_S1110 - Strasbourg, France