Remediation Program Via a "Serious Game" for the Cognitive Functions of Multiple Sclerosis Patients
Recruiting · NCT04694534 · Interventional (participants receive a specific treatment) · Lead sponsor: Lille Catholic University
View the official record on ClinicalTrials.gov →Interventions studied
Serious gameUsual HAS care
What this trial is about
The main goal of this study is to assess the effectiveness of a cognitive remediation program based on a "serious game" on the information processing speed evolution and the process of learning via episodic memory in multiple sclerosis patients.
Who can take part
Age range
18 Years to 65 Years
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Relapsing-remitting or progressive multiple sclerosis people defined according to Mc Donald's criteria revised in 2005
- Age between ≥ 18 and ≤ 65 years old
- Cognitive complaint, with at least one deficient score at the initial neuropsychological examination (\<5th percentile of the reference group), one of the scores of which concerns at least one BICAMS test
- Have not had a definite relapse for at least 6 weeks
- Be at least 4 weeks away from a corticosteroid bolus
- Lack of neuroleptic treatment
- Patient with an Internet connection
- Signed informed consent
Exclusion criteria
- Severe cognitive deficit defined by obtaining a deficit score in more than six cognitive processes at the initial neuropsychological assessment.
- Neuropsychological care
- Inability to receive oral and written information
- Inability to use the software (due in particular to motor and / or sensory difficulties),
- Neurological or psychiatric comorbidity, other than MS and anxiodepressive syndrome
- Patient with severe anxiodepressive syndrome (BDI\> 27)
- Participation in an interventional study on cognitive functions
- Patient under legal protection, guardianship or curatorship
- Pregnant or breastfeeding women
Where it is running
6 locations listed.
- CH Arras - Arras, Hauts-de-France, France
- CH LENS - Lens, Hauts-de-France, France
- CHRU - Lille, Hauts-de-France, France
- Saint Vincent hospital - Lille, Hauts-de-France, France
- Saint-Philibert hospital - Lomme, Nord, France
- Charles Nicolle Hospital - Rouen, Normandy, France