Systematic Assessment of Laryngopharyngeal Function in Patients With Neurodegenerative Diseases
Recruiting · NCT04706234 · Observational (researchers observe without assigning treatment) · Lead sponsor: Kliniken Beelitz GmbH
View the official record on ClinicalTrials.gov →What this trial is about
This is a non-interventional observational study designed to systematically record the results of routine laryngeal examinations and specific characteristics of dysphagia in patients with neurodegenerative disorders. The results of a fiberoptic / flexible endoscopic evaluation of swallowing (FEES) while performing a structured task protocol will be recorded. If available, laryngeal electromyography (EMG) results will also be recorded. In addition to the examination results, demographic and disease-specific data are collected, and two questionnaires, the Swallowing Disturbance Questionnaire for Parkinson's Disease (SDQ-PD) and the swallowing specific Quality Of Life Questionnaire (SWALQOL), are administered.
Who can take part
Inclusion criteria
- diagnosis of probable or possible multiple system atrophy according to current consensus criteria (Gilman et al. 2008) or
- diagnosis of probable or possible PSP according to the the Movement Disorders Society (MDS) diagnostic criteria (Höglinger et al. 2017) or
- diagnosis of Parkinson's disease according to the MDS diagnostic criteria (Postuma et al 2015)
- Hoehn and Yahr Stage within the range of I-V or
- diagnosis of motor neurone disease or
- diagnosis of a neurodegenerative disease other than specified above
- AND underwent laryngopharyngeal assessment according to the systematic task protocol during FEES (Warnecke et al. 2019).
Exclusion criteria
- \- Patients who do not sign the consent form
Where it is running
16 locations listed.
- IRCCS Istituto delle Scienze Neurologiche, Azienda USL di Bologna - Bologna, Italy
- Department of Neurology, Gifu University Graduate School of Medicine - Gifu, Japan
- Asklepios Klinik Barmbek - Hamburg, Germany
- Department of Neurology Asklepios Klinik Barmbek - Hamburg, Germany
- Department of Neurology SNUCM - Seoul, South Korea
- Department of Neurology, Movement Disorders Unit, Medical Center Tel Aviv - Tel Aviv, Israel
- Department of Neurology, Medical University Warsaw - Warsaw, Poland
- Department of Neurology, Medical University of Ulm - Ulm, Baden-Wurttemberg, Germany
- Movement Disorders Hospital - Kliniken Beelitz - Beelitz-Heilstätten, Brandenburg, Germany
- Unidad de Parkinson y Trastornos del Movimiento Instituto Clínic de Neurociencias, Hospital Clinic de Barcelona - Barcelona, Catalonia, Spain
- Department of Neurology, Medical School Hannover - Hanover, Lower Saxony, Germany
- Department of Neurology, University Hospital Münster - Münster, North Rhine-Westphalia, Germany
- Department of Neurology, University Hospital Carl Gustav Carus - Dresden, Saxony, Germany
- Department of Neueology Asklepios Klinik Stadtroda - Stadtroda, Thuringia, Germany
- Asklepios Fachklinikum Stadtroda - Stadtroda, Thuringia, Germany
- Department of Neurology and Department of ENT, Medical University Innsbruck - Innsbruck, Tyrol, Austria