Investigating Inhibitory Control Networks in Parkinson's Disease
Recruiting · NCT04735458 · Interventional (participants receive a specific treatment) · Lead sponsor: University of Alabama at Birmingham
View the official record on ClinicalTrials.gov →Interventions studied
What this trial is about
The purpose of this study is to investigate the brain activity associated with non-motor symptoms of movement disorders, including Parkinson's disease and essential tremor. These movement disorders commonly have significant non-motor features also, including depression, cognitive impairment, decreased attention, and slower processing speeds. The investigators are interested in the brain activity associated with these symptoms, and perform recordings of the surface of the brain, in addition to the typical recordings the investigators perform, during routine deep brain stimulation (DBS) surgery.
Who can take part
Inclusion criteria
- Eligible for surgery based on multi-disciplinary consensus review
- Have a diagnosis of Parkinson's disease or Essential Tremor
- Have a diagnosis of medically-refractory movement disorder (Parkinson's disease, Essential Tremor, or dystonia)
- Willingness to participate in the paradigms described in the protocol
Exclusion criteria
- Inability to provide full and informed consent
- Age younger than 18
- Are not able to participate in study-related activities
- History of prior ischemic/hemorrhagic stroke, subdural hemorrhage, or seizure
Where it is running
1 location listed across 1 US state.
- University of Alabama at Birmingham - Birmingham, Alabama, United States