Spinal Cord Lesion Detection in Multiple Sclerosis Using Novel MRI Sequences
Recruiting · NCT04819737 · Interventional (participants receive a specific treatment) · Lead sponsor: University Hospital, Basel, Switzerland
View the official record on ClinicalTrials.gov →Interventions studied
SC MRIpatient questionnaire
What this trial is about
This study is to evaluate the sensitivity and intra-/inter-observer agreement of the averaged magnetization inversion recovery acquisitions (AMIRA) in spinal cord (SC) Multiple sclerosis (MS) lesion detection and to evaluate the additional clinical value of this sequence in clinical settings.
Who can take part
Age range
18 Years and older
Sex
All (male and female)
Healthy volunteers
No - a diagnosis or condition is required
Phase
Not applicable (e.g. observational or device study)
Study type
Interventional (participants receive a specific treatment)
Inclusion criteria
- Diagnosis of multiple sclerosis according to established international criteria
- Steroid free period: \> 4 weeks
- Participation in the Swiss MS Cohort (SMSC) study
Exclusion criteria
- . History of severe (other) neurological, internal or psychiatric disease with SC affection
- MRI-related exclusion criteria (questionnaire):
- Paramagnetic and/or superparamagnetic foreign objects in the body (especially when located close to the SC)
- Pacemaker
- Claustrophobia
- Pregnancy, lactation
- Known hypersensitivity to gadolinium-based contrast media
Where it is running
1 location listed.
- University Hospital Basel, Department of Neurology - Basel, Switzerland